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Impact of Vanadium Complexes Treatment on the Oxidative Stress Factors in Wistar Rats Plasma
Joint Authors
Francik, R.
Librowski, T.
Krośniak, M.
Gryboś, R.
Barlik, M.
Kudła, A.
Source
Bioinorganic Chemistry and Applications
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-10-11
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Topics
Abstract EN
The aim of this study was to investigate the clinical efficacy of vanadium complexes on triglycerides (TG), total cholesterol (Chol), uric acid (UA), urea (U), and antioxidant parameters: nonenzymatic (FRAP—ferric reducing ability of plasma, and reduced glutathione—GSH) and enzymatic (glutathione peroxidase—GPx, catalase—CAT, and GPx/CAT ratio) activity in the plasma of healthy male Wistar rats.
Three vanadium complexes: [VO(bpy)2]SO4⋅2H2O, [VO(4,4′Me2bpy)2]SO4⋅2H2O, and Na[VO(O2)2(bpy)]⋅8H2O are administered by gavage during 5 weeks in two different diets such as control (C) and high fatty (F) diets.
Changes of biochemical and antioxidants parameters are measured in plasma.
All three vanadium complexes statistically decrease the body mass growth in comparison to the control and fatty diet.
In plasma GSH was statistically increased in all vanadium complexes-treated rats from control and fatty group in comparison to only control group.
Calculated GPX/CAT ratio was the highest in the control group in comparison to others.
American Psychological Association (APA)
Francik, R.& Krośniak, M.& Barlik, M.& Kudła, A.& Gryboś, R.& Librowski, T.. 2011. Impact of Vanadium Complexes Treatment on the Oxidative Stress Factors in Wistar Rats Plasma. Bioinorganic Chemistry and Applications،Vol. 2011, no. 2011, pp.1-8.
https://search.emarefa.net/detail/BIM-454436
Modern Language Association (MLA)
Francik, R.…[et al.]. Impact of Vanadium Complexes Treatment on the Oxidative Stress Factors in Wistar Rats Plasma. Bioinorganic Chemistry and Applications No. 2011 (2011), pp.1-8.
https://search.emarefa.net/detail/BIM-454436
American Medical Association (AMA)
Francik, R.& Krośniak, M.& Barlik, M.& Kudła, A.& Gryboś, R.& Librowski, T.. Impact of Vanadium Complexes Treatment on the Oxidative Stress Factors in Wistar Rats Plasma. Bioinorganic Chemistry and Applications. 2011. Vol. 2011, no. 2011, pp.1-8.
https://search.emarefa.net/detail/BIM-454436
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-454436