The Anticaries Effect of a Food Extract (Shiitake) in a Short-Term Clinical Study
Joint Authors
Wilson, Michael
Buijs, Mark J.
Hedelin, Pamie
Rosema, Martijn
Karbowiak, Aneta
Signoretto, Caterina
Hassan, Haidar
Lingström, Peter
Zaura, Egija
Spratt, David A.
Pratten, Jonathan
van der Weijden, Fridus
Daglia, Maria
Source
Journal of Biomedicine and Biotechnology
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-02-07
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
The main objective was to investigate whether low-molecular-weight fraction of edible mushroom shiitake extract (Lentinus edodes) possesses caries-preventive properties.
The study was designed as a double-blind, three-leg, cross-over, randomized, controlled clinical trial carried out on two series of volunteers at the University of Gothenburg, and the Academic Centre for Dentistry Amsterdam.
Volunteers rinsed twice daily with a solution containing low-molecular-weight fraction of edible mushroom, placebo (negative control without active ingredients), or Meridol (positive control, AmF-SnF2) for two weeks, with a two-week washout period between each rinsing period.
Changes in the acidogenicity of dental plaque before and after a sucrose challenge, shifts in microbial composition, and plaque scores were determined.
Frequent rinses with shiitake reduced the metabolic activity of dental plaque.
No reduction of plaque scores and no inhibition of the production of organic acids in plaque was found.
Minor differences in microbial composition between test sessions were found.
To conclude, the results indicate that shiitake extract has anticariogenic potential, but not to the same extent as the positive control.
American Psychological Association (APA)
Lingström, Peter& Zaura, Egija& Hassan, Haidar& Buijs, Mark J.& Hedelin, Pamie& Pratten, Jonathan…[et al.]. 2012. The Anticaries Effect of a Food Extract (Shiitake) in a Short-Term Clinical Study. Journal of Biomedicine and Biotechnology،Vol. 2012, no. 2012, pp.1-10.
https://search.emarefa.net/detail/BIM-455368
Modern Language Association (MLA)
Lingström, Peter…[et al.]. The Anticaries Effect of a Food Extract (Shiitake) in a Short-Term Clinical Study. Journal of Biomedicine and Biotechnology No. 2012 (2012), pp.1-10.
https://search.emarefa.net/detail/BIM-455368
American Medical Association (AMA)
Lingström, Peter& Zaura, Egija& Hassan, Haidar& Buijs, Mark J.& Hedelin, Pamie& Pratten, Jonathan…[et al.]. The Anticaries Effect of a Food Extract (Shiitake) in a Short-Term Clinical Study. Journal of Biomedicine and Biotechnology. 2012. Vol. 2012, no. 2012, pp.1-10.
https://search.emarefa.net/detail/BIM-455368
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-455368