Synthesis and Evaluation of Novel Pyrroles and Pyrrolopyrimidines as Anti-Hyperglycemic Agents

Joint Authors

Fathallah, Samar S.
Ali, S. A.
Abdelaziz, D. H. A.
Mohamed, M. S.

Source

BioMed Research International

Issue

Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-13, 13 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2014-06-26

Country of Publication

Egypt

No. of Pages

13

Main Subjects

Medicine

Abstract EN

A series of pyrrole and pyrrolopyrimidine derivatives were examined for their in vivo antihyperglycemic activity.

Compounds Ia–c,e, and IVg showed promising antihyperglycemic activity equivalent to a well-known standard antihyperglycemic drug, Glimepiride (Amaryl, 4 mg/kg).

In this paper, we examine and discuss the structure-activity relationships and antihyperglycemic activity of these compounds.

American Psychological Association (APA)

Mohamed, M. S.& Ali, S. A.& Abdelaziz, D. H. A.& Fathallah, Samar S.. 2014. Synthesis and Evaluation of Novel Pyrroles and Pyrrolopyrimidines as Anti-Hyperglycemic Agents. BioMed Research International،Vol. 2014, no. 2014, pp.1-13.
https://search.emarefa.net/detail/BIM-457336

Modern Language Association (MLA)

Mohamed, M. S.…[et al.]. Synthesis and Evaluation of Novel Pyrroles and Pyrrolopyrimidines as Anti-Hyperglycemic Agents. BioMed Research International No. 2014 (2014), pp.1-13.
https://search.emarefa.net/detail/BIM-457336

American Medical Association (AMA)

Mohamed, M. S.& Ali, S. A.& Abdelaziz, D. H. A.& Fathallah, Samar S.. Synthesis and Evaluation of Novel Pyrroles and Pyrrolopyrimidines as Anti-Hyperglycemic Agents. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-13.
https://search.emarefa.net/detail/BIM-457336

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-457336