Serum Cotinine Levels and Prehypertension in Never Smokers
Joint Authors
Burchfiel, Cecil
Xiao, Jie
Shankar, Anoop
Andrew, Michael E.
Alshaarawy, Omayma
Source
International Journal of Hypertension
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-02-17
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Background.
Few studies have shown that self-reported secondhand smoke exposure in never smokers is associated with high blood pressure.
However, there are no studies investigating the relationship between secondhand smoke exposure, measured objectively by serum cotinine levels, and high blood pressure in never smokers.
Methods.
We examined never smokers (n=2027) from the National Health and Nutrition Examination Survey 2005–2008.
Our exposure of interest was the secondhand smoke exposure estimated by serum cotinine level and our outcome was prehypertension (n=734), defined as a systolic blood pressure of 120–139 mmHg or diastolic blood pressure of 80–89 mmHg.
Results.
We found that, in never smokers, serum cotinine levels were positively associated with prehypertension.
Compared to those with cotinine levels in the lowest quartile (≤0.024 ng/mL), the multivariable odds ratio (95% confidence interval) of prehypertension among those with cotinine levels in the highest quartile (≥0.224 ng/mL) was 1.45(1.00, 2.11); P trend =0.0451.
In subsequent subgroup analyses, the positive association was found to be stronger among men, non-Whites, and non-obese subjects.
Conclusion.
Higher secondhand smoke exposure measured objectively by serum cotinine levels was found to be associated with prehypertension in certain subgroups of a representative sample of the US population.
American Psychological Association (APA)
Alshaarawy, Omayma& Xiao, Jie& Andrew, Michael E.& Burchfiel, Cecil& Shankar, Anoop. 2013. Serum Cotinine Levels and Prehypertension in Never Smokers. International Journal of Hypertension،Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-460284
Modern Language Association (MLA)
Alshaarawy, Omayma…[et al.]. Serum Cotinine Levels and Prehypertension in Never Smokers. International Journal of Hypertension No. 2013 (2013), pp.1-8.
https://search.emarefa.net/detail/BIM-460284
American Medical Association (AMA)
Alshaarawy, Omayma& Xiao, Jie& Andrew, Michael E.& Burchfiel, Cecil& Shankar, Anoop. Serum Cotinine Levels and Prehypertension in Never Smokers. International Journal of Hypertension. 2013. Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-460284
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-460284