(E)3-2-(1-(2,4-Dihydroxyphenyl)ethyldeneamino)phenyl)-2-methylquinazoline-4(3H)-one Schiff Base and Its Metal Complexes : A New Drug of Choice against Methicillin-Resistant Staphylococcus aureus
Joint Authors
Manikprabhu, Deene
Siddappa, K.
Mane, Sunilkumar B.
Source
Bioinorganic Chemistry and Applications
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-03-09
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
The 3-(2-aminophenyl) quinazolin-2-methyl-4(3H)-one and 2,4-dihydroxyacetophenone undergo condensation to afford (E)3-2-(1-(2,4-dihydroxyphenyl)ethyldeneamino)phenyl)-2-methylquinazoline-4(3H)-one Schiff base (DHPEAPMQ).
The newly synthesized Schiff base (DHPEAPMQ) and its metal complexes were evaluated for their antimicrobial activity against methicillin-resistant Staphylococcus aureus isolated from the Gulbarga region in India.
The Cu(II), Ni(II), and Zn(II) complexes of Schiff base (DHPEAPMQ) showed good antimicrobial activity.
So, this could be a new drug of choice.
American Psychological Association (APA)
Siddappa, K.& Mane, Sunilkumar B.& Manikprabhu, Deene. 2014. (E)3-2-(1-(2,4-Dihydroxyphenyl)ethyldeneamino)phenyl)-2-methylquinazoline-4(3H)-one Schiff Base and Its Metal Complexes : A New Drug of Choice against Methicillin-Resistant Staphylococcus aureus. Bioinorganic Chemistry and Applications،Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-464403
Modern Language Association (MLA)
Siddappa, K.…[et al.]. (E)3-2-(1-(2,4-Dihydroxyphenyl)ethyldeneamino)phenyl)-2-methylquinazoline-4(3H)-one Schiff Base and Its Metal Complexes : A New Drug of Choice against Methicillin-Resistant Staphylococcus aureus. Bioinorganic Chemistry and Applications No. 2014 (2014), pp.1-8.
https://search.emarefa.net/detail/BIM-464403
American Medical Association (AMA)
Siddappa, K.& Mane, Sunilkumar B.& Manikprabhu, Deene. (E)3-2-(1-(2,4-Dihydroxyphenyl)ethyldeneamino)phenyl)-2-methylquinazoline-4(3H)-one Schiff Base and Its Metal Complexes : A New Drug of Choice against Methicillin-Resistant Staphylococcus aureus. Bioinorganic Chemistry and Applications. 2014. Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-464403
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-464403
