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Implementation of a Parallel Protein Structure Alignment Service on Cloud
Joint Authors
Source
International Journal of Genomics
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-03-25
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Natural & Life Sciences (Multidisciplinary)
Biology
Abstract EN
Protein structure alignment has become an important strategy by which to identify evolutionary relationships between protein sequences.
Several alignment tools are currently available for online comparison of protein structures.
In this paper, we propose a parallel protein structure alignment service based on the Hadoop distribution framework.
This service includes a protein structure alignment algorithm, a refinement algorithm, and a MapReduce programming model.
The refinement algorithm refines the result of alignment.
To process vast numbers of protein structures in parallel, the alignment and refinement algorithms are implemented using MapReduce.
We analyzed and compared the structure alignments produced by different methods using a dataset randomly selected from the PDB database.
The experimental results verify that the proposed algorithm refines the resulting alignments more accurately than existing algorithms.
Meanwhile, the computational performance of the proposed service is proportional to the number of processors used in our cloud platform.
American Psychological Association (APA)
Hung, Che-Lun& Lin, Yaw-Ling. 2013. Implementation of a Parallel Protein Structure Alignment Service on Cloud. International Journal of Genomics،Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-472476
Modern Language Association (MLA)
Hung, Che-Lun& Lin, Yaw-Ling. Implementation of a Parallel Protein Structure Alignment Service on Cloud. International Journal of Genomics No. 2013 (2013), pp.1-8.
https://search.emarefa.net/detail/BIM-472476
American Medical Association (AMA)
Hung, Che-Lun& Lin, Yaw-Ling. Implementation of a Parallel Protein Structure Alignment Service on Cloud. International Journal of Genomics. 2013. Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-472476
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-472476