A Two-Stage Exon Recognition Model Based on Synergetic Neural Network

Joint Authors

Chen, Yidong
Huang, Zhehuang

Source

Computational and Mathematical Methods in Medicine

Issue

Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-7, 7 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2014-03-25

Country of Publication

Egypt

No. of Pages

7

Main Subjects

Medicine

Abstract EN

Exon recognition is a fundamental task in bioinformatics to identify the exons of DNA sequence.

Currently, exon recognition algorithms based on digital signal processing techniques have been widely used.

Unfortunately, these methods require many calculations, resulting in low recognition efficiency.

In order to overcome this limitation, a two-stage exon recognition model is proposed and implemented in this paper.

There are three main works.

Firstly, we use synergetic neural network to rapidly determine initial exon intervals.

Secondly, adaptive sliding window is used to accurately discriminate the final exon intervals.

Finally, parameter optimization based on artificial fish swarm algorithm is used to determine different species thresholds and corresponding adjustment parameters of adaptive windows.

Experimental results show that the proposed model has better performance for exon recognition and provides a practical solution and a promising future for other recognition tasks.

American Psychological Association (APA)

Huang, Zhehuang& Chen, Yidong. 2014. A Two-Stage Exon Recognition Model Based on Synergetic Neural Network. Computational and Mathematical Methods in Medicine،Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-476761

Modern Language Association (MLA)

Huang, Zhehuang& Chen, Yidong. A Two-Stage Exon Recognition Model Based on Synergetic Neural Network. Computational and Mathematical Methods in Medicine No. 2014 (2014), pp.1-7.
https://search.emarefa.net/detail/BIM-476761

American Medical Association (AMA)

Huang, Zhehuang& Chen, Yidong. A Two-Stage Exon Recognition Model Based on Synergetic Neural Network. Computational and Mathematical Methods in Medicine. 2014. Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-476761

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-476761