Extended Spectrum β-Lactamases among Gram-Negative Bacterial Isolates from Clinical Specimens in Three Major Hospitals in Northern Jordan
Joint Authors
Batchoun, Raymond G.
Swedan, Samer F.
Shurman, Abdullah M.
Source
International Journal of Microbiology
Issue
Vol. 2009, Issue 2009 (31 Dec. 2009), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2009-09-10
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Natural & Life Sciences (Multidisciplinary)
Medicine
Abstract EN
Background and Objectives.
Extended spectrum β-lactamase (ESBL) production is increasing all over the world, and organisms other than E.
coli and K.
pneumoniae are acquiring this character.
ESBL production is detectable by automation, E-test, double disk diffusion (DDD), and PCR.
This study aimed to determine the prevalence of ESBL production among clinical isolates of gram-negative rods, and to evaluate the effectiveness of augmentation of clavunate with Cefotaxime, Ceftazoxime, Aztreonam, Ceftriaxone, and Cefpodoxime in detecting ESBL production.
Methods.
472 clinical gram-negative isolates identified by standard methods were tested for ESBL-production by (DDD) method using six cephalosporins and amoxicillin-clavulinate discs.
Results.
108/472 (22.9%) of the isolates were ESBL producers, and were prevalent in tertiary care hospitals.
88.2% of E.
cloacae, 71.4% of K.
pneumoniae, 28.6% of K.
oxytoca, 12.5% of C.
freundii, 11.1% of A.
calcoacceticus, and 10.8% of E.
coli were ESBL producers.
The DDD test demonstrated some variations in the efficacy of the different cephalosporins in detecting all the ESBL producers.
The inclusion of ceftizoxime discs increased the efficacy of the test.
It is concluded that ESBL-producing bacteria were prevalent among our hospitalized patients, and involved genera other than Klebsiella and Escherichia, and the inclusion of ceftizoxime increased the efficacy of ESBL detection by the DDD test.
American Psychological Association (APA)
Batchoun, Raymond G.& Swedan, Samer F.& Shurman, Abdullah M.. 2009. Extended Spectrum β-Lactamases among Gram-Negative Bacterial Isolates from Clinical Specimens in Three Major Hospitals in Northern Jordan. International Journal of Microbiology،Vol. 2009, no. 2009, pp.1-8.
https://search.emarefa.net/detail/BIM-477650
Modern Language Association (MLA)
Batchoun, Raymond G.…[et al.]. Extended Spectrum β-Lactamases among Gram-Negative Bacterial Isolates from Clinical Specimens in Three Major Hospitals in Northern Jordan. International Journal of Microbiology No. 2009 (2009), pp.1-8.
https://search.emarefa.net/detail/BIM-477650
American Medical Association (AMA)
Batchoun, Raymond G.& Swedan, Samer F.& Shurman, Abdullah M.. Extended Spectrum β-Lactamases among Gram-Negative Bacterial Isolates from Clinical Specimens in Three Major Hospitals in Northern Jordan. International Journal of Microbiology. 2009. Vol. 2009, no. 2009, pp.1-8.
https://search.emarefa.net/detail/BIM-477650
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-477650