LDL-CHDL-C Ratio Predicts Carotid Intima-Media Thickness Progression Better Than HDL-C or LDL-C Alone
Joint Authors
Imaizumi, Tsutomu
Adachi, Hisashi
Yoshikawa, Kuniko
Kumagae, Shun-Ichi
Hirai, Yuji
Nanjo, Yasuki
Ohbu-Murayama, Kyoko
Fukami, Ako
Otsuka, Maki
Kumagai, Eita
Ogata, Kinuka
Satoh, Akira
Tsukagawa, Eri
Yokoi, Kanako
Kasahara, Akiko
Enomoto, Mika
Esaki, Eishi
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-07-05
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
High-density lipoprotein cholesterol (HDL-C) and low-density lipoprotein cholesterol (LDL-C) are strong predictors of atherosclerosis.
Statin-induced changes in the ratio of LDL-C to HDL-C (LDL-C/HDL-C) predicted atherosclerosis progression better than LDL-C or HDL-C alone.
However, the best predictor of subclinical atherosclerosis remains unknown.
Our objective was to investigate this issue by measuring changes in carotid intima-media thickness (IMT).
A total of 1,920 subjects received health examinations in 1999, and were followed up in 2007.
Changes in IMT (follow-up IMT/baseline IMT×100) were measured by ultrasonography.
Our results showed that changes in IMT after eight years were significantly related to HDL-C (inversely, P<0.05) and to LDL-C/HDL-C ratio (P<0.05).
When the LDL-C/HDL-C ratios were divided into quartiles, analysis of covariance showed that increases in the ratio were related to IMT progression (P<0.05).
This prospective study demonstrated the LDL-C/HDL-C ratio is a better predictor of IMT progression than HDL-C or LDL-C alone.
American Psychological Association (APA)
Enomoto, Mika& Adachi, Hisashi& Hirai, Yuji& Fukami, Ako& Satoh, Akira& Otsuka, Maki…[et al.]. 2011. LDL-CHDL-C Ratio Predicts Carotid Intima-Media Thickness Progression Better Than HDL-C or LDL-C Alone. Journal of Lipids،Vol. 2011, no. 2011, pp.1-6.
https://search.emarefa.net/detail/BIM-480632
Modern Language Association (MLA)
Enomoto, Mika…[et al.]. LDL-CHDL-C Ratio Predicts Carotid Intima-Media Thickness Progression Better Than HDL-C or LDL-C Alone. Journal of Lipids No. 2011 (2011), pp.1-6.
https://search.emarefa.net/detail/BIM-480632
American Medical Association (AMA)
Enomoto, Mika& Adachi, Hisashi& Hirai, Yuji& Fukami, Ako& Satoh, Akira& Otsuka, Maki…[et al.]. LDL-CHDL-C Ratio Predicts Carotid Intima-Media Thickness Progression Better Than HDL-C or LDL-C Alone. Journal of Lipids. 2011. Vol. 2011, no. 2011, pp.1-6.
https://search.emarefa.net/detail/BIM-480632
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-480632
