Labeling of Tannic Acid with Technetium-99m for Diagnosis of Stomach Ulcer

Joint Authors

Talaat, H. M.
Ibrahim, Ismail Taha
El-Tawoosy, M.

Source

ISRN Pharmaceutics

Issue

Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-6, 6 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2011-07-19

Country of Publication

Egypt

No. of Pages

6

Main Subjects

Pharmacy, Health & Medical Sciences
Pharmacology

Abstract EN

Tannic acid is a polyphenolic compound that could be labeled with technetium-99m.

To produce about 90% yield of 99mTc-tannic acid in acidic media (pH), the conditions required were 150 μg tin chloride, 30 min reaction time, and 200 μg of the substrate.

99mTc-tannic was stable for 6 h.

Oral biodistribution of 99mTc-tannic showed that it concentrated in the stomach ulcer to reach about 50% of the total injected dose at 1 h after orall administration.

This concentration of 99mTc-tannic in stomach ulcer may be sufficient to radio-image the presence of ulcer in the stomach.

American Psychological Association (APA)

Ibrahim, Ismail Taha& El-Tawoosy, M.& Talaat, H. M.. 2011. Labeling of Tannic Acid with Technetium-99m for Diagnosis of Stomach Ulcer. ISRN Pharmaceutics،Vol. 2011, no. 2011, pp.1-6.
https://search.emarefa.net/detail/BIM-482236

Modern Language Association (MLA)

Ibrahim, Ismail Taha…[et al.]. Labeling of Tannic Acid with Technetium-99m for Diagnosis of Stomach Ulcer. ISRN Pharmaceutics No. 2011 (2011), pp.1-6.
https://search.emarefa.net/detail/BIM-482236

American Medical Association (AMA)

Ibrahim, Ismail Taha& El-Tawoosy, M.& Talaat, H. M.. Labeling of Tannic Acid with Technetium-99m for Diagnosis of Stomach Ulcer. ISRN Pharmaceutics. 2011. Vol. 2011, no. 2011, pp.1-6.
https://search.emarefa.net/detail/BIM-482236

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-482236