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Labeling of Tannic Acid with Technetium-99m for Diagnosis of Stomach Ulcer
Joint Authors
Talaat, H. M.
Ibrahim, Ismail Taha
El-Tawoosy, M.
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-07-19
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Pharmacy, Health & Medical Sciences
Pharmacology
Abstract EN
Tannic acid is a polyphenolic compound that could be labeled with technetium-99m.
To produce about 90% yield of 99mTc-tannic acid in acidic media (pH), the conditions required were 150 μg tin chloride, 30 min reaction time, and 200 μg of the substrate.
99mTc-tannic was stable for 6 h.
Oral biodistribution of 99mTc-tannic showed that it concentrated in the stomach ulcer to reach about 50% of the total injected dose at 1 h after orall administration.
This concentration of 99mTc-tannic in stomach ulcer may be sufficient to radio-image the presence of ulcer in the stomach.
American Psychological Association (APA)
Ibrahim, Ismail Taha& El-Tawoosy, M.& Talaat, H. M.. 2011. Labeling of Tannic Acid with Technetium-99m for Diagnosis of Stomach Ulcer. ISRN Pharmaceutics،Vol. 2011, no. 2011, pp.1-6.
https://search.emarefa.net/detail/BIM-482236
Modern Language Association (MLA)
Ibrahim, Ismail Taha…[et al.]. Labeling of Tannic Acid with Technetium-99m for Diagnosis of Stomach Ulcer. ISRN Pharmaceutics No. 2011 (2011), pp.1-6.
https://search.emarefa.net/detail/BIM-482236
American Medical Association (AMA)
Ibrahim, Ismail Taha& El-Tawoosy, M.& Talaat, H. M.. Labeling of Tannic Acid with Technetium-99m for Diagnosis of Stomach Ulcer. ISRN Pharmaceutics. 2011. Vol. 2011, no. 2011, pp.1-6.
https://search.emarefa.net/detail/BIM-482236
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-482236