Role of IL-33 and Its Receptor in T Cell-Mediated Autoimmune Diseases

Joint Authors

Chen, Guangjie
Zhao, Qing

Source

BioMed Research International

Issue

Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-10, 10 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2014-06-16

Country of Publication

Egypt

No. of Pages

10

Main Subjects

Medicine

Abstract EN

Interleukin-33 (IL-33) is a new cytokine of interleukin-1 family, whose specific receptor is ST2.

IL-33 exerts its functions via its target cells and plays different roles in diseases.

ST2 deletion and exclusion of IL-33/ST2 axis are accompanied by enhanced susceptibility to dominantly T cell-mediated organ-specific autoimmune diseases.

It has been reported that IL-33/ST2 pathway plays a key role in host defense and immune regulation in inflammatory and infectious diseases.

This review focuses on new findings in the roles of IL-33 and ST2 in several kinds of T cell-mediated autoimmune diseases.

American Psychological Association (APA)

Zhao, Qing& Chen, Guangjie. 2014. Role of IL-33 and Its Receptor in T Cell-Mediated Autoimmune Diseases. BioMed Research International،Vol. 2014, no. 2014, pp.1-10.
https://search.emarefa.net/detail/BIM-483032

Modern Language Association (MLA)

Zhao, Qing& Chen, Guangjie. Role of IL-33 and Its Receptor in T Cell-Mediated Autoimmune Diseases. BioMed Research International No. 2014 (2014), pp.1-10.
https://search.emarefa.net/detail/BIM-483032

American Medical Association (AMA)

Zhao, Qing& Chen, Guangjie. Role of IL-33 and Its Receptor in T Cell-Mediated Autoimmune Diseases. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-10.
https://search.emarefa.net/detail/BIM-483032

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-483032