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Long-Term Use of Probiotic-Containing Yogurts Is a Safe Way to Prevent Helicobacter pylori : Based on a Mongolian Gerbil's Model
Joint Authors
Lu, Chien-Yu
Kuo, Fu-Chen
Wang, Sophie S. W.
Chang, Lin-Li
Weng, Bi-Chuang
Liu, Chung-Jung
Kuo, Chao-Hung
Wu, Chun-Chieh
Tsai, Pei-Yun
Cheng, Kuang-Hung
Lee, Tsung-Cheng
Chen, Li-Wei
Hu, Huang-Ming
Wu, Deng-Chyang
Source
Biochemistry Research International
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-11-21
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Background.
The suppression of Helicobacter pylori (H.
pylori) decreases H.
pylori-related diseases.
The probiotics have an inhibitory effect on H.
pylori.
Aim.
We investigated the effects of long-term use of yogurt on H.
pylori based on Mongolian gerbils’ model.
Materials and Methods.
Yogurt (containing a supplement of Lactobacillus acidophilus, Bifidobacterium lactis, etc.) was used.
Forty-six gerbils were divided into five groups.
All groups were inoculated with H.
pylori for 5 to 8 weeks.
The yogurt was given as follows: Group (Gr.) A: from 1st to 4th week; Gr.
B from 5th to 8th week; Gr.
C: from 17th week to sacrifice; Gr.
D: from 5th week to sacrifice.
Gerbils were sacrificed on the 52nd week.
Histology was evaluated according to the Sydney system.
Results.
The positive rates of H.
pylori were 60% (Gr.
A), 75% (Gr.
B), 67% (Gr.
C), 44% (Gr.
D), and 100% (Gr.
E).
Gr.
D showed lower inflammatory score.
Only Gr.
E (60%) had intestinal metaplasia.
Gr.
D showed higher IL-10 and lower TNF-α expression than Gr.
E.
Conclusion.
Long-term intake of yogurt could decrease H.
pylori infection.
The long-term use of yogurt would be an alternative strategy to manage H.
pylori infection.
American Psychological Association (APA)
Kuo, Chao-Hung& Wang, Sophie S. W.& Lu, Chien-Yu& Hu, Huang-Ming& Kuo, Fu-Chen& Weng, Bi-Chuang…[et al.]. 2013. Long-Term Use of Probiotic-Containing Yogurts Is a Safe Way to Prevent Helicobacter pylori : Based on a Mongolian Gerbil's Model. Biochemistry Research International،Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-483634
Modern Language Association (MLA)
Kuo, Chao-Hung…[et al.]. Long-Term Use of Probiotic-Containing Yogurts Is a Safe Way to Prevent Helicobacter pylori : Based on a Mongolian Gerbil's Model. Biochemistry Research International No. 2013 (2013), pp.1-7.
https://search.emarefa.net/detail/BIM-483634
American Medical Association (AMA)
Kuo, Chao-Hung& Wang, Sophie S. W.& Lu, Chien-Yu& Hu, Huang-Ming& Kuo, Fu-Chen& Weng, Bi-Chuang…[et al.]. Long-Term Use of Probiotic-Containing Yogurts Is a Safe Way to Prevent Helicobacter pylori : Based on a Mongolian Gerbil's Model. Biochemistry Research International. 2013. Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-483634
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-483634