Iron Inhibits Respiratory Burst of Peritoneal Phagocytes In Vitro

Joint Authors

Klein, Andrzej
Kubit, Piotr
Jurek, Aleksandra
Gotfryd, Kamil
Turyna, Bohdan

Source

ISRN Urology

Issue

Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-5, 5 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2011-12-08

Country of Publication

Egypt

No. of Pages

5

Main Subjects

Diseases
Medicine

Abstract EN

Objective.

This study examines the effects of iron ions Fe3+ on the respiratory burst of phagocytes isolated from peritoneal effluents of continuous ambulatory peritoneal dialysis (CAPD) patients, as an in vitro model of iron overload in end-stage renal disease (ESRD).

Material and Methods.

Respiratory burst of peritoneal phagocytes was measured by chemiluminescence method.

Results.

At the highest used concentration of iron ions Fe3+ (100 μM), free radicals production by peritoneal phagocytes was reduced by 90% compared to control.

Conclusions.

Iron overload may increase the risk of infectious complications in ESRD patients.

American Psychological Association (APA)

Gotfryd, Kamil& Jurek, Aleksandra& Kubit, Piotr& Klein, Andrzej& Turyna, Bohdan. 2011. Iron Inhibits Respiratory Burst of Peritoneal Phagocytes In Vitro. ISRN Urology،Vol. 2011, no. 2011, pp.1-5.
https://search.emarefa.net/detail/BIM-484485

Modern Language Association (MLA)

Gotfryd, Kamil…[et al.]. Iron Inhibits Respiratory Burst of Peritoneal Phagocytes In Vitro. ISRN Urology No. 2011 (2011), pp.1-5.
https://search.emarefa.net/detail/BIM-484485

American Medical Association (AMA)

Gotfryd, Kamil& Jurek, Aleksandra& Kubit, Piotr& Klein, Andrzej& Turyna, Bohdan. Iron Inhibits Respiratory Burst of Peritoneal Phagocytes In Vitro. ISRN Urology. 2011. Vol. 2011, no. 2011, pp.1-5.
https://search.emarefa.net/detail/BIM-484485

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-484485