Shear Stress, Energy Losses, and Costs : A Resolved Dilemma of Pulsatile Cardiac Assist Devices
Joint Authors
Chachques, Juan Carlos
Wang, Qinmei
Carbognani, Daniel
Wu, Guifu
Yang, Daya
Dai, Gang
Liu, Jia
Nour, Sayed
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-01-08
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
Cardiac assist devices (CAD) cause endothelial dysfunction with considerable morbidity.
Employment of pulsatile CAD remains controversial due to inadequate perfusion curves and costs.
Alternatively, we are proposing a new concept of pulsatile CAD based on a fundamental revision of the entire circulatory system in correspondence with the physiopathology and law of physics.
It concerns a double lumen disposable tube device that could be adapted to conventional cardiopulmonary bypass (CPB) and/or CAD, for inducing a homogenous, downstream pulsatile perfusion mode with lower energy losses.
In this study, the device’s prototypes were tested in a simulated conventional pediatric CPB circuit for energy losses and as a left ventricular assist device (LVAD) in ischemic piglets model for endothelial shear stress (ESS) evaluations.
In conclusion and according to the study results the pulsatile tube was successfully capable of transforming a conventional CPB and/or CAD steady flow into a pulsatile perfusion mode, with nearly physiologic pulse pressure and lower energy losses.
This represents a cost-effective promising method with low mortality and morbidity, especially in fragile cardiac patients.
American Psychological Association (APA)
Nour, Sayed& Liu, Jia& Dai, Gang& Carbognani, Daniel& Yang, Daya& Wu, Guifu…[et al.]. 2014. Shear Stress, Energy Losses, and Costs : A Resolved Dilemma of Pulsatile Cardiac Assist Devices. BioMed Research International،Vol. 2014, no. 2014, pp.1-12.
https://search.emarefa.net/detail/BIM-488350
Modern Language Association (MLA)
Nour, Sayed…[et al.]. Shear Stress, Energy Losses, and Costs : A Resolved Dilemma of Pulsatile Cardiac Assist Devices. BioMed Research International No. 2014 (2014), pp.1-12.
https://search.emarefa.net/detail/BIM-488350
American Medical Association (AMA)
Nour, Sayed& Liu, Jia& Dai, Gang& Carbognani, Daniel& Yang, Daya& Wu, Guifu…[et al.]. Shear Stress, Energy Losses, and Costs : A Resolved Dilemma of Pulsatile Cardiac Assist Devices. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-12.
https://search.emarefa.net/detail/BIM-488350
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-488350