MRI-Based Multiscale Model for Electromagnetic Analysis in the Human Head with Implanted DBS
Joint Authors
Iacono, Maria Ida
Angelone, Leonardo M.
Makris, Nikos
Bonmassar, Giorgio
Mainardi, Luca
Source
Computational and Mathematical Methods in Medicine
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-07-15
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
Deep brain stimulation (DBS) is an established procedure for the treatment of movement and affective disorders.
Patients with DBS may benefit from magnetic resonance imaging (MRI) to evaluate injuries or comorbidities.
However, the MRI radio-frequency (RF) energy may cause excessive tissue heating particularly near the electrode.
This paper studies how the accuracy of numerical modeling of the RF field inside a DBS patient varies with spatial resolution and corresponding anatomical detail of the volume surrounding the electrodes.
A multiscale model (MS) was created by an atlas-based segmentation using a 1 mm3 head model (mRes) refined in the basal ganglia by a 200 μm2 ex-vivo dataset.
Four DBS electrodes targeting the left globus pallidus internus were modeled.
Electromagnetic simulations at 128 MHz showed that the peak of the electric field of the MS doubled (18.7 kV/m versus 9.33 kV/m) and shifted 6.4 mm compared to the mRes model.
Additionally, the MS had a sixfold increase over the mRes model in peak-specific absorption rate (SAR of 43.9 kW/kg versus 7 kW/kg).
The results suggest that submillimetric resolution and improved anatomical detail in the model may increase the accuracy of computed electric field and local SAR around the tip of the implant.
American Psychological Association (APA)
Iacono, Maria Ida& Makris, Nikos& Mainardi, Luca& Angelone, Leonardo M.& Bonmassar, Giorgio. 2013. MRI-Based Multiscale Model for Electromagnetic Analysis in the Human Head with Implanted DBS. Computational and Mathematical Methods in Medicine،Vol. 2013, no. 2013, pp.1-12.
https://search.emarefa.net/detail/BIM-491164
Modern Language Association (MLA)
Iacono, Maria Ida…[et al.]. MRI-Based Multiscale Model for Electromagnetic Analysis in the Human Head with Implanted DBS. Computational and Mathematical Methods in Medicine No. 2013 (2013), pp.1-12.
https://search.emarefa.net/detail/BIM-491164
American Medical Association (AMA)
Iacono, Maria Ida& Makris, Nikos& Mainardi, Luca& Angelone, Leonardo M.& Bonmassar, Giorgio. MRI-Based Multiscale Model for Electromagnetic Analysis in the Human Head with Implanted DBS. Computational and Mathematical Methods in Medicine. 2013. Vol. 2013, no. 2013, pp.1-12.
https://search.emarefa.net/detail/BIM-491164
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-491164