Leukocyte Counts, Myeloperoxidase, and Pregnancy-Associated Plasma Protein A as Biomarkers for Cardiovascular Disease : Towards a Multi-Biomarker Approach
Joint Authors
Passos, Valéria Lima
Lobbes, M. B. I.
Daemen, M. J. A. P.
Lutgens, E.
Rousch, M.
Heeneman, S.
Braat, S. H. J. G.
Kooi, M. E.
Ruiters, A. W.
Ten Cate, H.
van Engelshoven, J. M. A.
Source
International Journal of Vascular Medicine
Issue
Vol. 2010, Issue 2010 (31 Dec. 2010), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-05-30
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
We evaluated leukocyte counts and levels of CRP, fibrinogen, MPO, and PAPP-A in patients with stable and unstable angina pectoris, acute myocardial infarction, and healthy controls.
All biomarkers were analyzed again after 6 months.
Leukocyte counts and concentrations of fibrinogen, CRP, MPO, and PAPP-A were significantly increased in patients with acute myocardial infarction.
Leukocyte counts and concentrations of MPO were significantly increased in patients with unstable angina pectoris compared with controls.
After 6 months, leukocyte counts and MPO concentrations were still increased in patients with acute myocardial infarction when compared to controls.
Discriminant analysis showed that leukocyte counts, MPO, and PAPP-A concentrations classified study group designation for acute coronary events correctly in 83% of the cases.
In conclusion, combined assessment of leukocyte counts, MPO, and PAPP-A was able to correctly classify acute coronary events, suggesting that this could be a promising panel for a multibiomarker approach to assess cardiovascular risk.
American Psychological Association (APA)
Lobbes, M. B. I.& Kooi, M. E.& Lutgens, E.& Ruiters, A. W.& Passos, Valéria Lima& Braat, S. H. J. G.…[et al.]. 2010. Leukocyte Counts, Myeloperoxidase, and Pregnancy-Associated Plasma Protein A as Biomarkers for Cardiovascular Disease : Towards a Multi-Biomarker Approach. International Journal of Vascular Medicine،Vol. 2010, no. 2010, pp.1-9.
https://search.emarefa.net/detail/BIM-493733
Modern Language Association (MLA)
Lobbes, M. B. I.…[et al.]. Leukocyte Counts, Myeloperoxidase, and Pregnancy-Associated Plasma Protein A as Biomarkers for Cardiovascular Disease : Towards a Multi-Biomarker Approach. International Journal of Vascular Medicine No. 2010 (2010), pp.1-9.
https://search.emarefa.net/detail/BIM-493733
American Medical Association (AMA)
Lobbes, M. B. I.& Kooi, M. E.& Lutgens, E.& Ruiters, A. W.& Passos, Valéria Lima& Braat, S. H. J. G.…[et al.]. Leukocyte Counts, Myeloperoxidase, and Pregnancy-Associated Plasma Protein A as Biomarkers for Cardiovascular Disease : Towards a Multi-Biomarker Approach. International Journal of Vascular Medicine. 2010. Vol. 2010, no. 2010, pp.1-9.
https://search.emarefa.net/detail/BIM-493733
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-493733
