Oncologic Outcomes of Asian Men with Clinically Localized Prostate Cancer after Extraperitoneal Laparoscopic Radical Prostatectomy : A Single-Institution Experience
Joint Authors
Huang, Chao-Yuan
Lai, Ming-Kuen
Chueh, Shih-Chieh Jeff
Tai, Huai-Ching
Huang, Kuo-How
Chung, Shiu-Dong
Yu, Hong-Jeng
Wang, Shuo-Meng
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-12-19
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Purpose.
To evaluate the midterm oncologic results of extraperitoneal laparoscopic radical prostatectomy (EPLRP) for Asian men with localized prostate cancer.
Methods.
Between 2004 and 2009, 218 men underwent EPLRP at an Asian tertiary hospital.
The mean preoperative prostate-specific antigen (PSA) was 15.5 ng/ml and mean Gleason score was 6.6.
Stage distributions were cT1a-b in 21 cases, cT1c in 139, cT2 in 48 and cT3 in 10.
Disease recurrence was defined as PSA ≥ 0.2 ng/mL in 2 consecutive measurements or initiation of secondary therapy.
Results.
Postoperative pathological stage was pT2a-b in 33 patients, pT2cN0 in 10, pT3a in 27, pT3b in 36, pT4 in 9 and pN1 in 10.
Positive surgical margins occurred in 14.6% and 48.6% for pT2 and pT3 diseases, respectively (P<.001).
The overall PSA recurrence-free survival at 3 and 5 years was 82.1% and 74.5%.
By the pathological stages, 3-year recurrence-free survival was 92.4% (pT2), 81.1% (pT3a), 62.6% (pT3b-4) and 55.6% (pN1), respectively (P<.001).
Conclusions.
EPLRP is curative even for some locally advanced prostate cancers in a midterm follow-up.
Even at an Asian center of low volume of radical prostatectomy EPLRP still provides oncologic outcomes similar to that of high volume centers.
American Psychological Association (APA)
Tai, Huai-Ching& Lai, Ming-Kuen& Huang, Chao-Yuan& Wang, Shuo-Meng& Huang, Kuo-How& Chung, Shiu-Dong…[et al.]. 2010. Oncologic Outcomes of Asian Men with Clinically Localized Prostate Cancer after Extraperitoneal Laparoscopic Radical Prostatectomy : A Single-Institution Experience. Prostate Cancer،Vol. 2011, no. 2011, pp.1-7.
https://search.emarefa.net/detail/BIM-495600
Modern Language Association (MLA)
Tai, Huai-Ching…[et al.]. Oncologic Outcomes of Asian Men with Clinically Localized Prostate Cancer after Extraperitoneal Laparoscopic Radical Prostatectomy : A Single-Institution Experience. Prostate Cancer No. 2011 (2011), pp.1-7.
https://search.emarefa.net/detail/BIM-495600
American Medical Association (AMA)
Tai, Huai-Ching& Lai, Ming-Kuen& Huang, Chao-Yuan& Wang, Shuo-Meng& Huang, Kuo-How& Chung, Shiu-Dong…[et al.]. Oncologic Outcomes of Asian Men with Clinically Localized Prostate Cancer after Extraperitoneal Laparoscopic Radical Prostatectomy : A Single-Institution Experience. Prostate Cancer. 2010. Vol. 2011, no. 2011, pp.1-7.
https://search.emarefa.net/detail/BIM-495600
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-495600