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Predictive Factors of Response in HER2-Positive Breast Cancer Treated by Neoadjuvant Therapy
Joint Authors
Guiu, S.
Coudert, B.
Toure, M.
Mouret Reynier, M. A.
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-04-29
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Since 2005, major progresses have been made in the neoadjuvant treatment of HER2-positive breast cancer.
Trastuzumab introduction associated with chemotherapy has been the first major step leading to the improvement of the complete pathological response rate and, like in the adjuvant studies, better survivals.
Dual HER2 blockade has been the next step and trastuzumab is associated now with other anti-HER2 therapies like lapatinib or pertuzumab, the latter being much more easy to use in combination with chemotherapy.
Additional knowledge is necessary to better define within the HER2 tumor subgroup which patients could benefit more from targeted therapies.
Different biomarkers have been studied to predict the response after anti-HER2 neoadjuvant therapies but until now none has been validated.
American Psychological Association (APA)
Guiu, S.& Mouret Reynier, M. A.& Toure, M.& Coudert, B.. 2013. Predictive Factors of Response in HER2-Positive Breast Cancer Treated by Neoadjuvant Therapy. Journal of Oncology،Vol. 2013, no. 2013, pp.1-9.
https://search.emarefa.net/detail/BIM-503583
Modern Language Association (MLA)
Guiu, S.…[et al.]. Predictive Factors of Response in HER2-Positive Breast Cancer Treated by Neoadjuvant Therapy. Journal of Oncology No. 2013 (2013), pp.1-9.
https://search.emarefa.net/detail/BIM-503583
American Medical Association (AMA)
Guiu, S.& Mouret Reynier, M. A.& Toure, M.& Coudert, B.. Predictive Factors of Response in HER2-Positive Breast Cancer Treated by Neoadjuvant Therapy. Journal of Oncology. 2013. Vol. 2013, no. 2013, pp.1-9.
https://search.emarefa.net/detail/BIM-503583
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-503583