HMG-CoA Reductase Inhibitors from Monascus-Fermented Rice

Joint Authors

Liu, Chunli
Li, Xuemei
Guo, Shuren
Duan, Zhenwen

Source

Journal of Chemistry

Issue

Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-6, 6 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2013-11-24

Country of Publication

Egypt

No. of Pages

6

Main Subjects

Chemistry

Abstract EN

Seven compounds were isolated from Monascus-fermented rice by column chromatography with silica gel and semiprep HPLC.

Their structures were elucidated by extensive spectroscopic methods.

All compounds displayed HMG-CoA reductase inhibitory potential, among them compound 7 exhibited strong inhibition with IC50 value comparable with lovastatin.

In this study, two compounds (1 and 2) were obtained from natural source for the first time.

American Psychological Association (APA)

Li, Xuemei& Liu, Chunli& Duan, Zhenwen& Guo, Shuren. 2013. HMG-CoA Reductase Inhibitors from Monascus-Fermented Rice. Journal of Chemistry،Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-505071

Modern Language Association (MLA)

Li, Xuemei…[et al.]. HMG-CoA Reductase Inhibitors from Monascus-Fermented Rice. Journal of Chemistry No. 2013 (2013), pp.1-6.
https://search.emarefa.net/detail/BIM-505071

American Medical Association (AMA)

Li, Xuemei& Liu, Chunli& Duan, Zhenwen& Guo, Shuren. HMG-CoA Reductase Inhibitors from Monascus-Fermented Rice. Journal of Chemistry. 2013. Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-505071

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-505071