Synthesis and Bioevaluation of Novel Imatinib Base Derivatives via 1,1′-Carbonyldiimidazole Catalyst
Joint Authors
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-11-07
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
A series of eleven compounds were synthesized from 6-methyl-N′-(4-(pyridine-3-yl)pyrimidin-2-yl)benzene-1,3-diamine with various substituted carboxylic acid under solvent-free conditions using 1,1′-carbonyldiimidazole (CDI) as a catalyst.
The yields of compounds are more than 72%.
All the compounds were characterized by physical, spectroscopic, and elemental analysis.
Compound 8b exhibited good inhibition towards antimicrobial activity compared to the other compounds.
American Psychological Association (APA)
Patoliya, M. J.& Kharadi, G. J.. 2013. Synthesis and Bioevaluation of Novel Imatinib Base Derivatives via 1,1′-Carbonyldiimidazole Catalyst. Journal of Chemistry،Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-507772
Modern Language Association (MLA)
Patoliya, M. J.& Kharadi, G. J.. Synthesis and Bioevaluation of Novel Imatinib Base Derivatives via 1,1′-Carbonyldiimidazole Catalyst. Journal of Chemistry No. 2013 (2013), pp.1-7.
https://search.emarefa.net/detail/BIM-507772
American Medical Association (AMA)
Patoliya, M. J.& Kharadi, G. J.. Synthesis and Bioevaluation of Novel Imatinib Base Derivatives via 1,1′-Carbonyldiimidazole Catalyst. Journal of Chemistry. 2013. Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-507772
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-507772
