Meal Replacements for Weight Loss in Type 2 Diabetes in a Community Setting
Joint Authors
Keogh, Jennifer B.
Clifton, Peter M.
Source
Journal of Nutrition and Metabolism
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-10-02
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Background.
There is limited information on the effectiveness of meal replacements (MRs) as a weight-loss strategy in an unsupervised community setting.
Aim.
To evaluate the use of MR compared with a diet book for 6 months.
Subjects and Methods.
Obese subjects (n=120) with type 2 diabetes mellitus were recruited from the community in Adelaide, South Australia, and randomised to intervention or control.
Subjects in the intervention were advised to consume 2 MR/day for 3 months and 1 MR/day for 3 months and follow the manufacturers’ instructions from printed material and the website.
Subjects in the control arm were given a commercially available diet book.
Results.
Consumption of 2 MR for 3 months and 1 MR for the subsequent 3 months led to weight loss of 5.5 kg (5%) and a 0.26% decrease in HbA1c while the diet book group had a weight loss of 3 kg (3%) (P=0.027 for difference between groups) and a decrease in HbA1c of 0.15% (between group ns) in those who completed the 6-month study.
On intention-to-treat (last observation carried forward) weight loss at 6 months was 3.4 kg in MR and 1.8 kg in control (P=0.07).
Decreases in HbA1c were 0.22% and 0.12%, respectively (P=ns).
HDL cholesterol increased by 4% in MR and decreased by 1% in control (P=0.004).
Blood pressure decreased equally in both groups.
There were reductions in fasting glucose in both groups at 6 months with no changes in LDL-cholesterol or triglyceride concentrations.
Conclusion.
MR confers benefits in HbA1C reduction and weight loss at 6 months in those who completed the study.
American Psychological Association (APA)
Keogh, Jennifer B.& Clifton, Peter M.. 2012. Meal Replacements for Weight Loss in Type 2 Diabetes in a Community Setting. Journal of Nutrition and Metabolism،Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-508091
Modern Language Association (MLA)
Keogh, Jennifer B.& Clifton, Peter M.. Meal Replacements for Weight Loss in Type 2 Diabetes in a Community Setting. Journal of Nutrition and Metabolism No. 2012 (2012), pp.1-7.
https://search.emarefa.net/detail/BIM-508091
American Medical Association (AMA)
Keogh, Jennifer B.& Clifton, Peter M.. Meal Replacements for Weight Loss in Type 2 Diabetes in a Community Setting. Journal of Nutrition and Metabolism. 2012. Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-508091
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-508091