Antioxidant and cytotoxic activities of essential oil of Ocimum canum sims. from India
Joint Authors
Selvi, M. Tamil
Thirugnanasampandan, R.
Sundarammal, S.
Source
Journal of Saudi Chemical Society
Issue
Vol. 19, Issue 1 (31 Jan. 2015), pp.97-100, 4 p.
Publisher
Publication Date
2015-01-31
Country of Publication
Saudi Arabia
No. of Pages
4
Main Subjects
Topics
Abstract EN
Chemical composition analysis of essential oil isolated fromthe leaves of OcimumcanumSims.
reported the presence of thirty six compounds.
The major compound was camphor (39.77 %).
In vitro antioxidant activity of the isolated oil showed dose dependent free radical scavenging activity against DPPH (IC50 523.55±0.001 lg/mL) and hydroxyl radicals (491.12±0.002 lg / mL), metal chelating (781.38±0.001 lg / mL) and prevention of deoxyribose degradation (168.50±0.003 lg / mL) activities were also calculated.
Antioxidant activity of oil was less observed when compared with positive controls such as ascorbic acid and BHT (12.49±0.002 and 30.14±0.005, respectively).
Significant cytotoxicity (IC50 value of 60 lg / mL) and DNA fragmentation was observed in breast cancer cells (MCF-7).
American Psychological Association (APA)
Selvi, M. Tamil& Thirugnanasampandan, R.& Sundarammal, S.. 2015. Antioxidant and cytotoxic activities of essential oil of Ocimum canum sims. from India. Journal of Saudi Chemical Society،Vol. 19, no. 1, pp.97-100.
https://search.emarefa.net/detail/BIM-518170
Modern Language Association (MLA)
Selvi, M. Tamil…[et al.]. Antioxidant and cytotoxic activities of essential oil of Ocimum canum sims. from India. Journal of Saudi Chemical Society Vol. 19, no. 1 (Jan. 2015), pp.97-100.
https://search.emarefa.net/detail/BIM-518170
American Medical Association (AMA)
Selvi, M. Tamil& Thirugnanasampandan, R.& Sundarammal, S.. Antioxidant and cytotoxic activities of essential oil of Ocimum canum sims. from India. Journal of Saudi Chemical Society. 2015. Vol. 19, no. 1, pp.97-100.
https://search.emarefa.net/detail/BIM-518170
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 100
Record ID
BIM-518170