Werner's syndrome

Abstract EN

Werner’s syndrome is a rare autosomal recessive premature aging syndrome, characterized primarily by a short stature, premature graying of the hair, balding, and trophic ulceration of legs.

Other features include scleroderma-like skin changes, beak shaped nose, high-pitched voice, stocky trunk with slender extremities, cataract, diabetes mellitus, atherosclerosis, osteoporosis, hypogonadism, and calcification of ligaments, tendons and subcutaneous tissue.

A 38-year-old man patient with Werners syndrome, presenting with ulcers of legs and plantar skin, premature canities, juvenile cataract, and atrophic skin of limbs is described