Glycemic disturbances in diabetic and non-diabetic patients undergoing hemodialysis

Abstract EN

Chronic kidney disease is a significant risk factor for the development of metabolic disturbance with or without presence of diabetes mellitus, this metabolic disturbance should be considered an important patient safety outcome in patients on hemodialysis, thus this cross- sectional study aimed to determine the effect of end stage renal failure on the blood glucose level in hemodialysis patients with or without diabetes mellitus and correlate of these parameters with the presence or absence of glycemic changes during hemodialysis.

In this blood samples was assayed in 60 participants : 20 patients with end-stage kidney disease with type II diabetes mellitus (group I), 20 with end-stage kidney disease without diabetes mellitus (group II) and 20 with healthy volunteers (group III, control).Different availableassays were used for blood glucose and the glycated hemoglobin.

In this no significant difference was found in the post prandial of patients groups and control group.

The glycosylated hemoglobin and fasting blood glucose significantly differed between patients groups and control group.

The fasting blood glucose was significantly different between group I and II.

It can be concluded from this study that glycated hemoglobin and fasting blood glucose strongly correlate with intra dialysis changes in patients with diabetes mellitus and non-diabetic patients.

This finding indicates the importance of careful assessment and control of glycaemia during hemodialysis.