Detection and prevalence of inducible clindamycin resistance in clinical and nasal carriage Staphylococcus aureus isolates in Jordan
Other Title(s)
كشف و انتشار بكتريا المكورات العنقودية المحفزة لمقاومة الكليندامايسين من عينات مرضيه و أنفية ناقلة لها في الأردن
Dissertant
al-Jarajirah, Dua Abd al-Karim
Thesis advisor
Comitee Members
al-Shakanbah, Jumah Muti
al-Tarawinah, Khalid Ahmad
Khulayfat, Khalid
University
Mutah University
Faculty
Faculty of Science
Department
Department of Biological Sciences
University Country
Jordan
Degree
Master
Degree Date
2015
English Abstract
Seventy one S.
aureus isolates were included in this study, of which Fifty five (77.5%) were MRSA.
67.3% of MRSA were hospital associated (HA-MRSA) while CA-MRSA were represented 32.7%.
Among MRSA, forty five isolates were resistant to erythromycin.
The presence of inducible clindamycin resistance was confirmed by the D-test for forty three (95.5%) erythromycin resistant MRSA.
Thirty three (76.7%) discordant exhibited the iMLSB phenotype, two (4.7%) the MSB and eight (18.6%) the cMLSB phenotypes.
Induction of clindamycin resistance was 1.6 times greater in CA-MRSA than in HA-MRSA (p = 0.014).
Significant prevalence was found for ermA and ermC among HA-MRSA and CAMRSA, respectively.
This is the first study in which the prevalence rate of iMLSB phenotypes in Jordan with genotypic surveillance was estimated with reinforcement on the role of erm genes in incidence of MLSB phenotypes.
Therefore, a continuous surveillance of MLSB resistance in MRSA (both community and hospitals) is of great importance before prescription of clindamycin MRSA treatment.
Main Subjects
Topics
No. of Pages
39
Table of Contents
Table of contents.
Abstract.
Abstract in Arabic.
Chapter One : Theoretical background.
Chapter Two : Literature review.
Chapter Three : Materials and methods.
Chapter Four : Result and discussion.
Conclusions.
References.
American Psychological Association (APA)
al-Jarajirah, Dua Abd al-Karim. (2015). Detection and prevalence of inducible clindamycin resistance in clinical and nasal carriage Staphylococcus aureus isolates in Jordan. (Master's theses Theses and Dissertations Master). Mutah University, Jordan
https://search.emarefa.net/detail/BIM-656398
Modern Language Association (MLA)
al-Jarajirah, Dua Abd al-Karim. Detection and prevalence of inducible clindamycin resistance in clinical and nasal carriage Staphylococcus aureus isolates in Jordan. (Master's theses Theses and Dissertations Master). Mutah University. (2015).
https://search.emarefa.net/detail/BIM-656398
American Medical Association (AMA)
al-Jarajirah, Dua Abd al-Karim. (2015). Detection and prevalence of inducible clindamycin resistance in clinical and nasal carriage Staphylococcus aureus isolates in Jordan. (Master's theses Theses and Dissertations Master). Mutah University, Jordan
https://search.emarefa.net/detail/BIM-656398
Language
English
Data Type
Arab Theses
Record ID
BIM-656398
