Association of hla-drb1 alleles and basal cell carcinoma (BCC)‎ of the skin in Basrah

Joint Authors

al-Hamdi, Khalil I.
Sayhud, Wasan A. A.
Hassuni, Hasan J.

Source

Basrah Journal of Surgery

Issue

Vol. 22, Issue 1 (30 Jun. 2016), pp.91-93, 3 p.

Publisher

University of Basrah College of Medicine

Publication Date

2016-06-30

Country of Publication

Iraq

No. of Pages

3

Main Subjects

Medicine

Abstract EN

Immunogenetic factors have been explored as being a possible risk factor in the aetiology of basal cell carcinoma (BCC).

This study aimed to clarify the association of HLA- DRB1 alleles in immunocompetent patients with BCC in Basrah city.

A total of 27 patients with confirmed BCC and 31 controls were analyzed for HLA-DRB1 genotyping using generic SSP2LB one lambda micro ssp- HLA-DNA typing tray.

Results showed a positive association of BCC with HLA DRB1*07 (p-value 0.0280, OR = 3.7143, 95 % CI=1.1521-11.9743), HLA alleles of DRB1*11 (OR = 2.2), DRB1*04(OR = 1.4), DRB1*01(OR = 1.125) have a higher frequency among cases but the association is not significant.

These finding suggest a possible immunogenetic role in the development of BCC.

American Psychological Association (APA)

Sayhud, Wasan A. A.& Hassuni, Hasan J.& al-Hamdi, Khalil I.. 2016. Association of hla-drb1 alleles and basal cell carcinoma (BCC) of the skin in Basrah. Basrah Journal of Surgery،Vol. 22, no. 1, pp.91-93.
https://search.emarefa.net/detail/BIM-697962

Modern Language Association (MLA)

Sayhud, Wasan A. A.…[et al.]. Association of hla-drb1 alleles and basal cell carcinoma (BCC) of the skin in Basrah. Basrah Journal of Surgery Vol. 22, no. 1 (Jun. 2016), pp.91-93.
https://search.emarefa.net/detail/BIM-697962

American Medical Association (AMA)

Sayhud, Wasan A. A.& Hassuni, Hasan J.& al-Hamdi, Khalil I.. Association of hla-drb1 alleles and basal cell carcinoma (BCC) of the skin in Basrah. Basrah Journal of Surgery. 2016. Vol. 22, no. 1, pp.91-93.
https://search.emarefa.net/detail/BIM-697962

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references : p. 93

Record ID

BIM-697962