Cardiac complications of homozygous-β thalassaemia
Other Title(s)
مخالطات مرض القلب بسبب ثلاسيميا المتجانسة نوع ب
Joint Authors
Salih, Khalaf A.
al-Khayru, Khalid Nafi Mustafa
Shaykhu, Sabri K.
Source
Issue
Vol. 3, Issue 2 (31 Dec. 2009), pp.31-41, 11 p.
Publisher
University of Duhok College of Medicine
Publication Date
2009-12-31
Country of Publication
Iraq
No. of Pages
11
Main Subjects
Pharmacy, Health & Medical Sciences
Abstract EN
Background Homozygous – β thalassaemia has frequently been reported to be associated with cardiac complications mainly due to the deposition of iron in the heart.
Objective To find effects of homozygous β-thalassemia on cardiac functions and its relation with Haemosiderosis.
Patients and Methods Eighty patients with h omo zygous β thalasseamia were included in the study.
Thalassaemic center attach to Ibn-Alatheer paediatric hospital, Haematology unit, Coronary care unit and Echo unit in Ibn-Sina teaching hospital in Mosul (February to September 2005).
All patients were subjected to full clinical, laboratory, ECG and Echocardiographic evaluat Results There were 50 males and 30 females.
Age ranged between 11-35 years, their mean was 15.8 years.
18 (22.5%) patients had cardiac dysfunction, of them 12 (15%) had systolic dysfunction and 6 (7.5%) had diastolic dysfunction.
ECG changes were present in 27(33.75%) patients and 31(38.75%) had valvular abnormalities.
Congestive heart failure present in 3(3.75%) patients and 3(3.75%) patients had pulmonary hypertension.
Conclusion Cardiac Complications are common in Homozygous-β Thalassaemia older than the age of 10 years.
Further studies utilizing more advanced techniques to detect earlier cardiac dysfunction more accurately may be useful.
American Psychological Association (APA)
Shaykhu, Sabri K.& al-Khayru, Khalid Nafi Mustafa& Salih, Khalaf A.. 2009. Cardiac complications of homozygous-β thalassaemia. Duhok Medical Journal،Vol. 3, no. 2, pp.31-41.
https://search.emarefa.net/detail/BIM-723011
Modern Language Association (MLA)
Shaykhu, Sabri K.…[et al.]. Cardiac complications of homozygous-β thalassaemia. Duhok Medical Journal Vol. 3, no. 2 (2009), pp.31-41.
https://search.emarefa.net/detail/BIM-723011
American Medical Association (AMA)
Shaykhu, Sabri K.& al-Khayru, Khalid Nafi Mustafa& Salih, Khalaf A.. Cardiac complications of homozygous-β thalassaemia. Duhok Medical Journal. 2009. Vol. 3, no. 2, pp.31-41.
https://search.emarefa.net/detail/BIM-723011
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 37-39
Record ID
BIM-723011