Effect of hemodialysis on oxidants and antioxidant factors in chronic renal failure
Joint Authors
Qorbani, Mustafa
Mehrpour, Golbarg
Rahimzadeh, Mitra
Azimzadeh, Muhammad Mahdi
Mirmiranpour, Husayn
Tajbakhsh, Ramin
Source
Saudi Journal of Kidney Diseases and Transplantation
Issue
Vol. 28, Issue 3 (30 Jun. 2017), pp.507-516, 10 p.
Publisher
Saudi Center for Organ Transplantation
Publication Date
2017-06-30
Country of Publication
Saudi Arabia
No. of Pages
10
Main Subjects
Topics
Abstract EN
The current study was conducted to assess the effect of hemodialysis (HD) on the status of plasma oxidants and antioxidants among patients with end-stage renal disease (ESRD).
These parameters can have an influence on the HD process and can also be useful for follow-up of these patients.
The participants of this cross-sectional study comprised 91 patients with a mean age of 51.1 ± 8.2 years on chronic HD with kt/v between 1.2 and 1.4.
The etiology of ESRD in these patients was as follows: diabetes mellitus in 39, hypertension in 35, and glomerulonephritis in 17 patients.
All patients were on maintenance treatment with phosphate binder, 1,25 Vitamin D, iron, and erythropoietin therapy as per the K/DOQI guidelines.
They were selected by random method from Shahid Bahonar Hospital, Karaj, Iran.
The height, weight, waist circumference (WC), and blood pressure were measured according to standardized protocols, and blood samples were obtained before and after HD.
Blood samples were checked for advanced glycation end products, advanced oxidation protein product, malondialdehyde (MDA), oxidized low-density lipoprotein (ox-LDL), and ferritin reducing ability of plasma, catalase, glutathione peroxidase (GPx), superoxide dismutase (SOD), and blood urea nitrogen (BUN).
The means of MDA, BUN, advanced glycation end product (AGE), and ox-LDL plasma level postdialysis significantly decreased compared to the predialysis level.
The mean of plasma catalase, GPx, and SOD increased significantly postdialysis compared to the predialysis level in these patients.
Factors including age, body mass index, WC, and diastolic blood pressure affected changes in levels of oxidants and antioxidants after HD.
Our study results oxidants and antioxidants during HD were assessed.
American Psychological Association (APA)
Tajbakhsh, Ramin& Qorbani, Mustafa& Mehrpour, Golbarg& Rahimzadeh, Mitra& Azimzadeh, Muhammad Mahdi& Mirmiranpour, Husayn. 2017. Effect of hemodialysis on oxidants and antioxidant factors in chronic renal failure. Saudi Journal of Kidney Diseases and Transplantation،Vol. 28, no. 3, pp.507-516.
https://search.emarefa.net/detail/BIM-767417
Modern Language Association (MLA)
Tajbakhsh, Ramin…[et al.]. Effect of hemodialysis on oxidants and antioxidant factors in chronic renal failure. Saudi Journal of Kidney Diseases and Transplantation Vol. 28, no. 3 (May. / Jun. 2017), pp.507-516.
https://search.emarefa.net/detail/BIM-767417
American Medical Association (AMA)
Tajbakhsh, Ramin& Qorbani, Mustafa& Mehrpour, Golbarg& Rahimzadeh, Mitra& Azimzadeh, Muhammad Mahdi& Mirmiranpour, Husayn. Effect of hemodialysis on oxidants and antioxidant factors in chronic renal failure. Saudi Journal of Kidney Diseases and Transplantation. 2017. Vol. 28, no. 3, pp.507-516.
https://search.emarefa.net/detail/BIM-767417
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 514-516
Record ID
BIM-767417