دور فيتامين ه في الوقاية من التأثيرات النسجية المرضية التي تسببها خلات الرصاص في أعضاء سمكة البلطي أحمر البطن Coptodon zillii (Gervais, 1848)‎

Abstract EN

The present study evaluates the role of a specific dose of vitamin E for reducing the histopathological effects induced lead acetate in organs of fish Coptodon zillii (gills, liver, kidney and intestines).

These fish, ninety in number, were brought to the laboratory and divided, after been adapted, into three groups each group consisted of sixteen fish put them into two repeating which contained eight of fish for each.

The first and second groups exposed to the concentration of 11 mg liter of lead acetate, the third group is control group.The first group and control group fed on a diet free of the vitamin E while the second group fed on diet contains a concentration of 300 mg kg diet of vitamin E.

The results showed that lead acetate led to large and diverse changes in organs of fish of the first group.

The form of gills changes of secondary gill lamellae, with bleeding, hyperplasia, swelling epithelial cells and detachment of epithelium of secondary gill lamellae observed, either in the liver which show large areas of cells suffer from the ballooning degeneration and massive hepatic necrosis.There are other possible changes such as dysplasia and infiltration of inflammatory cells.

In kidney there are degeneration of cells of most distal and proximal convoluted tubule with disappearance of brush boarder of the latter, necrosis of epithelial, sloughing cells, atrophy of the glomeruli and expansion of Bowman space.While in the intestines, degeneration and necrosis of the epithelium and the disintegration of the connective tissue of the lamellae propria and hyperplasia in submucosa are observed.

When fish of the second group feeding on the diet containing vitamin E, the severity of changes in the organs of fish decreased significantly, despite the presence of lead acetate .

As observed decline in the spread of histopathological effects as well as the lack of diversity and the emergence of minor changes in the four fish-organs.

This confirms that the concentration of 300 mg vitamin E per kg of diet is effective in reducing the histpathological effects caused by lead and has a protective role of diseases and reduce the development of histpathological effects.