Design and synthesis of two triazoninecarbaldehyde derivatives using several chemical tools
Joint Authors
Figueroa Valverde, Lauro
Dıaz Cedillo, Francisco, Francisco
Garcıa Cervera, Elodia
Pool Gomez, Eduardo
Rosas Nexticapa, Marcela
Lopez Ramos, Marıa
Vera Escobedo, Maria Isabel
Source
Journal of Saudi Chemical Society
Issue
Vol. 22, Issue 2 (28 Feb. 2018), pp.183-197, 15 p.
Publisher
Publication Date
2018-02-28
Country of Publication
Saudi Arabia
No. of Pages
15
Main Subjects
Abstract EN
Several triazonine-carbaldehyde derivatives have been prepared using different protocols ; however, some require special reagents and conditions.
The aim of study involved the synthesis of two triazonine-carbaldehyde derivative using testosterone or OTBS-testosterone as chemical tool.
Triazonine-carbaldehyde derivatives were prepared by a series of reactions that involve the following : (1) synthesis of two nitrobenzamide derivatives by reaction of testosterone or OTBS-testosterone with p-nitrobenzoyl azide using Copper(II) as catalyst ; (2) reaction of the nitrobenzamides with ethylenediamine to form two triazonine derivatives using boric acid as catalyst; (3) preparation of hexynyl-triazonine derivatives by the reaction of two triazonines 6-chlorohex-1-yne in basic medium ; (4) reaction of hexynyl-triazonine derivatives with benzaldehyde to form two triazoninol analogs ; (5) preparation of triazoninynal derivatives through oxidation of triazoninol analogs with dimethyl sulfoxide ; and (6) synthesis of triazonine-carbaldehyde derivatives by the reaction of triazoninynal derivatives with hexyne-1 using Copper(II) as catalyst.
The chemical structure of compounds was determined by spectroscopic and spectrometric methods.
In conclusion, in this work were prepared two triazoninone derivatives using several hemical techniques, which are simple procedures and easy to handle.
American Psychological Association (APA)
Figueroa Valverde, Lauro& Dıaz Cedillo, Francisco, Francisco& Garcıa Cervera, Elodia& Pool Gomez, Eduardo& Rosas Nexticapa, Marcela& Lopez Ramos, Marıa…[et al.]. 2018. Design and synthesis of two triazoninecarbaldehyde derivatives using several chemical tools. Journal of Saudi Chemical Society،Vol. 22, no. 2, pp.183-197.
https://search.emarefa.net/detail/BIM-782277
Modern Language Association (MLA)
Figueroa Valverde, Lauro…[et al.]. Design and synthesis of two triazoninecarbaldehyde derivatives using several chemical tools. Journal of Saudi Chemical Society Vol. 22, no. 2 (Feb. 2018), pp.183-197.
https://search.emarefa.net/detail/BIM-782277
American Medical Association (AMA)
Figueroa Valverde, Lauro& Dıaz Cedillo, Francisco, Francisco& Garcıa Cervera, Elodia& Pool Gomez, Eduardo& Rosas Nexticapa, Marcela& Lopez Ramos, Marıa…[et al.]. Design and synthesis of two triazoninecarbaldehyde derivatives using several chemical tools. Journal of Saudi Chemical Society. 2018. Vol. 22, no. 2, pp.183-197.
https://search.emarefa.net/detail/BIM-782277
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 196-197
Record ID
BIM-782277