Insulin autoimmune syndrome as a rare cause of hypoglycemia : a case report

Abstract EN

Most cases of recurrent hypoglycemia occur in patients with diabetes mellitus, while hypoglycemia is an uncommon clinical problem in a non diabetic patients.1 It can occur in the fasting or postprandial state, and needs evaluation.

This is a case of insulin autoimmune syndrome (IAS) in a Syrian woman with recurrent hypoglycemia.

Insulin autoimmune syndrome (IAS) is a rare cause of hyperinsulinemic hypoglycemia characterized by auto-antibodies to endogenous insulin in individuals without previous exposure to exogenous insulin.

Distinction from insulinoma is especially crucial to prevent unwarranted invasive procedures and surgical interventions in hypoglycemic patients