Macrophage activation syndrome in a patient with systemic-onset juvenile idiopathic arthritis initially treated for atypical kawasaki disease : a case-based review
Joint Authors
Hariri, Isa
Demachkieh, Rawan
Naja, Ahmad
Wakim, Gerard
Hashim, Ahmad
Source
Issue
Vol. 66, Issue 1 (31 Mar. 2018), pp.49-53, 5 p.
Publisher
Publication Date
2018-03-31
Country of Publication
Lebanon
No. of Pages
5
Main Subjects
Abstract EN
Systemic-onset juvenile idiopathic arthritis (SoJIA) is the most common rheumatic disorder in children and its presentation can mimic atypical Kawasaki disease.
The diagnosis of SoJIA is often challenging and children are often diagnosed and treated for Kawasaki disease initially, especially after an unremitting fever lasting for several days.
This fact can delay the treatment of SoJIA as incorrect treatment with intravenous immunoglobulins (IVIG) is being given and this may probably lead to a worse outcome in those individuals.
This is a case of a 12-month-old infant who was initially treated for atypical Kawasaki instead of a SoJIA presenting with a macrophage activating syndrome (MAS).
We also present a review of the literature that supports the diagnosis of SoJIA presenting with MAS.
Abstract FRE
L’arthrite juvénile idiopathique systémique (AJIS) est la pathologies rhumatologique la plus fréquente chez l’enfant avec une présentation pouvant souvent imiter une manifestation atypique de la maladie de Kawasaki.
Établir un diagnostic peut s’avérer compliqué.
Les enfants affectés sont le plus souvent diagnostiqués porteurs d’une maladie de Kawasaki et traités initialement par des immunoglobulines intraveineuses (IGIVs).
Avec pour conséquence directe de retarder, parfois de plusieurs jours, l’initiation d’un traitement efficace avant qu’un diagnostic correct soit établi.
à noter également que des IGIVs administrées à un patient atteint d’AJIS peuvent aggraver ses symptômes et précipiter une détérioration de son état clinique.
Nous rapportons le cas d’un enfant âgé de 12 mois traité initialement pour une présentation atypique de Kawasaki et qui s’est avéré atteint d’AJIS avec un syndrome d’activation macrophagique.
La revue de littérature qui suit le cas que nous rapportons confirme la complexité d'un tel diagnostic.
American Psychological Association (APA)
Hariri, Isa& Demachkieh, Rawan& Naja, Ahmad& Hashim, Ahmad& Wakim, Gerard. 2018. Macrophage activation syndrome in a patient with systemic-onset juvenile idiopathic arthritis initially treated for atypical kawasaki disease : a case-based review. Journal Médical Libanais،Vol. 66, no. 1, pp.49-53.
https://search.emarefa.net/detail/BIM-834941
Modern Language Association (MLA)
Hashim, Ahmad…[et al.]. Macrophage activation syndrome in a patient with systemic-onset juvenile idiopathic arthritis initially treated for atypical kawasaki disease : a case-based review. Journal Médical Libanais Vol. 66, no. 1 (Mar. 2018), pp.49-53.
https://search.emarefa.net/detail/BIM-834941
American Medical Association (AMA)
Hariri, Isa& Demachkieh, Rawan& Naja, Ahmad& Hashim, Ahmad& Wakim, Gerard. Macrophage activation syndrome in a patient with systemic-onset juvenile idiopathic arthritis initially treated for atypical kawasaki disease : a case-based review. Journal Médical Libanais. 2018. Vol. 66, no. 1, pp.49-53.
https://search.emarefa.net/detail/BIM-834941
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 53
Record ID
BIM-834941
