Phenolic acid content, antioxidant and cytotoxic activities of four Kalanchoe species
Joint Authors
Szewczyk, Katarzyna
Bogucka-Kocka, Anna
Zidorn, Christian
Kasprzycka, Małgorzata
Szymczak, Grazyna
Source
Saudi Journal of Biological Sciences
Issue
Vol. 25, Issue 4 (31 May. 2018), pp.622-630, 9 p.
Publisher
Publication Date
2018-05-31
Country of Publication
Saudi Arabia
No. of Pages
9
Main Subjects
Topics
Abstract EN
Phenolic acid composition, antioxidant, and cytotoxic activities in leaves of four Kalanchoe (Crassulaceae) species were evaluated.
Determination of phenolic acid contents were conducted by an optimized LC–ESI-MS /MS method.
The results show that Kalanchoe daigremontiana Raym.-Hamet & H.
Perrier (using ASE extraction) and Kalanchoe pinnata (Lam.) Pers.
contain the highest amounts of phenolic acids, while Kalanchoe nyikae Engl.
the lowest ones.
Among phenolic acids ferulic, caffeic and protocatechuic acids were occurring in the highest quantities in the analysed species.
The greatest amounts of ferulic and protocatechuic acids were found in K.
daigremontiana and K.
pinnata.
Moreover, the antiradical and cytotoxic activities of Kalanchoe extracts were investigated.
All tested extracts possessed antioxidant activity.
The obtained IC50 values (lg /mL) ranged from 49.9 lg /mL to 1410 lg/mL, indicating a large variation of the activity of the analysed extracts.
Cytotoxicity assays revealed dose-dependent effects in the cells lines tested.
Only K.
pinnata extract showed a high cytotoxicity against the H-9 human T cell line.
Other extracts (K.
daigremontiana, Kalanchoe milloti, K.
nyikae) showed more pronounced cytotoxicity towards J45.01 cells (human acute lymphoblastic leukaemia T cells).
The present study demonstrated that Kalanchoe extracts have significant antioxidant and cytotoxic effects.
This suggests that these species can be used as new sources of natural antioxidants and potential anticancer compounds.
American Psychological Association (APA)
Bogucka-Kocka, Anna& Zidorn, Christian& Kasprzycka, Małgorzata& Szymczak, Grazyna& Szewczyk, Katarzyna. 2018. Phenolic acid content, antioxidant and cytotoxic activities of four Kalanchoe species. Saudi Journal of Biological Sciences،Vol. 25, no. 4, pp.622-630.
https://search.emarefa.net/detail/BIM-838473
Modern Language Association (MLA)
Szewczyk, Katarzyna…[et al.]. Phenolic acid content, antioxidant and cytotoxic activities of four Kalanchoe species. Saudi Journal of Biological Sciences Vol. 25, no. 4 (May. 2018), pp.622-630.
https://search.emarefa.net/detail/BIM-838473
American Medical Association (AMA)
Bogucka-Kocka, Anna& Zidorn, Christian& Kasprzycka, Małgorzata& Szymczak, Grazyna& Szewczyk, Katarzyna. Phenolic acid content, antioxidant and cytotoxic activities of four Kalanchoe species. Saudi Journal of Biological Sciences. 2018. Vol. 25, no. 4, pp.622-630.
https://search.emarefa.net/detail/BIM-838473
Data Type
Journal Articles
Language
English
Record ID
BIM-838473