Chemical studies of flavonoids isolated from Palestinian plants : catmint, crataegus and fenugreek
Other Title(s)
دراسة مركبات الفلافونويد المستخلصة من النباتات الفلسطينية : القطرم، الزعرور و الحلبة
Dissertant
Thesis advisor
University
Birzeit University
Faculty
Faculty of Science
Department
Department of Chemistry
University Country
Palestine (West Bank)
Degree
Master
Degree Date
2018
English Abstract
Catmint (Nepeta curviflora) is a commonly used medicinal plant native to the Middle East.
In the first part of this research, Nepeta curviflora was extracted followed by chemical analysis and identification of its flavonoids.
Currently, only limited information is available about the chemical constituents of this plant species.
From aerial parts of catmint (Nepeta curviflora) the novel flavone O-glucuronides, ester forms of apigenin 7-O--glucuronopyranosyl-2’’-O-(2”’- O-caffeoyl)--glucuronopyranoside (1) and luteolin 7-O--glucuronopyranosyl-2’’-O-(2”’-O- (caffeoyl)--glucuronopyranoside (2) have been identified.
In addition, ester derivatives of phenolic compounds of rosmarinic acid (3) and caffeic acid (4) have been identified.
The isolated compounds were characterized using Ultra violet -visible spectroscopy (UV-Vis) and extensive use of one-dimensional nuclear magnetic resonance spectroscopy (1D-NMR) and two-dimensional nuclear magnetic resonance spectroscopy (2D-NMR).
In the second part of this research, activated zinc using ultrasound has been introduced as a new tool for reductive reaction to modify flavonoids of fenugreek and Crataegus to anthocyanins.
In-vitro, anti-bacterial activity of original fenugreek, modified fenugreek, original Crataegus and modified Crataegus were investigated against three gram-positive (Staphylococcus aureus, Bacillus subtilis and Staphylococcus epidermidis) and three gram-negative bacteria (Escherichia coli, Proteus mirabilis and Pseudomonas aeruginosa) using agar diffusion method.
Unfortunately, all tested sample didn’t show any anti-bacterial activity against all types of gramnegative and gram-positive bacteria.
Main Subjects
Topics
No. of Pages
65
Table of Contents
Table of contents.
Abstract.
Abstract in Arabic.
Chapter One : Introduction.
Chapter Two : Experimental.
Chapter Three : Results and discussion.
Chapter Four : Conclusion.
Chapter Five : Recommendation.
References.
American Psychological Association (APA)
Rabi, Maysa. (2018). Chemical studies of flavonoids isolated from Palestinian plants : catmint, crataegus and fenugreek. (Master's theses Theses and Dissertations Master). Birzeit University, Palestine (West Bank)
https://search.emarefa.net/detail/BIM-889348
Modern Language Association (MLA)
Rabi, Maysa. Chemical studies of flavonoids isolated from Palestinian plants : catmint, crataegus and fenugreek. (Master's theses Theses and Dissertations Master). Birzeit University. (2018).
https://search.emarefa.net/detail/BIM-889348
American Medical Association (AMA)
Rabi, Maysa. (2018). Chemical studies of flavonoids isolated from Palestinian plants : catmint, crataegus and fenugreek. (Master's theses Theses and Dissertations Master). Birzeit University, Palestine (West Bank)
https://search.emarefa.net/detail/BIM-889348
Language
English
Data Type
Arab Theses
Record ID
BIM-889348
