Determination of phylogenetic groups and antimicrobial susce-ptibility patterns for Escherichia coli isolated from patients with urinary tract infection

Abstract EN

Escherichia coli (E.

coli) are one of the most widespread microbes in the world, capable to cause intestinal or extraintestinal disease and lead to a wide range of diseases.

This study was conducted to isolate E.

coli from urine of patients with urinary tract infections at Al-HusseinTeaching Hospital, during the period from November 2017 to March 2018, to detect Phylogenetic groups for isolates and susceptibility to antibiotic.

A total of 152 samples were collected from urine gave 46 (30%) E.

coli.

Phylogenetic analysis based on the presence or absence of chuA, yjaA and TspE4.C2 marker genes, was carried out to 46 isolates of UPEC, showed that Phylogenetic group B2 was most predominant, which included 34(74%) isolates, group A 6(13%) isolates and group D 6(13%) isolates.

Antibiotic resistance exhibited group B2 was resistance 100% to amoxicillin/clavulanic acidacid, 94% trimethoprim, 82% tetracycline and ceftriaxon 76%.

Group A and D 100% resistance for each of the amoxicillin/clavulanic acid, trimethoprim and tetracycline.

Group A resistance 33% to ceftriaxone and group D was 100%.

In This study the phylogentic group B2 the majority predominated in UPEC and more resistance to antimicrobial.