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Fabricating hierarchical ZSM-5 to induct long chain antioxidant coenzyme Q10 for biomedical application
Joint Authors
Jermy, B. Rabindran
Ravinayagam, Vijaya
Source
Journal of Saudi Chemical Society
Issue
Vol. 23, Issue 4 (31 May. 2019), pp.461-476, 16 p.
Publisher
Publication Date
2019-05-31
Country of Publication
Saudi Arabia
No. of Pages
16
Main Subjects
Topics
Abstract EN
The study investigates the hydrophobic antioxidant Coenzyme Q10 (CoQ10) adsorption over industrially relevant hierarchical ZSM-5 for potential therapeutic applications.
The designing of hierarchical nanocomposites was optimized with two different NaOH/CTAB ratios (0.18 and 0.62) over ZSM-5 (SiO2/Al2O3 = 22–27) of different crystal sizes (0.5 mm, 2.0 mm and 3.0 mm) and different SiO2/Al2O3 ratios (23, 80, 280 and 1500) through top-down approach.
Hydrothermal stability of samples was studied using 100% water steam at 700 C and 750 C for 2 h, respectively.
Reassembling nano ZSM-5 into hierarchical composite was found to exhibit ordered/disordered hexagonal mesophase depending on alkaline treated ZSM-5 crystal sizes and silica to alumina ratios.
The phase changes were analyzed using different textural characterizations such as X-ray diffraction, BET surface area, ammonia desorption technique, 27Al MAS NMR, thermogravimetric analysis and transmission electron microscope.
21 different nanoformulations were screened for CoQ10 adsorption and subsequently selected samples were applied for curcumin and ascorbic acid adsorption.
Hierarchical ZSM-5 with SiO2/Al2O3 ratio 80 (ZSM-5-80 (0.62)) was found to be steam stable and optimum with highest Q10 adsorption (55%).
The adsorption influence over different crystal size and silica to alumina ratios, clearly showed the dependency over synergistic action of textural characteristics such as external surface area, pore volume, and weak acidity.
The structured nanosupports with pore sizes between 3 and 4.0 nm were found to exhibit highest CoQ10 adsorption.
American Psychological Association (APA)
Ravinayagam, Vijaya& Jermy, B. Rabindran. 2019. Fabricating hierarchical ZSM-5 to induct long chain antioxidant coenzyme Q10 for biomedical application. Journal of Saudi Chemical Society،Vol. 23, no. 4, pp.461-476.
https://search.emarefa.net/detail/BIM-893489
Modern Language Association (MLA)
Ravinayagam, Vijaya& Jermy, B. Rabindran. Fabricating hierarchical ZSM-5 to induct long chain antioxidant coenzyme Q10 for biomedical application. Journal of Saudi Chemical Society Vol. 23, no. 4 (May. 2019), pp.461-476.
https://search.emarefa.net/detail/BIM-893489
American Medical Association (AMA)
Ravinayagam, Vijaya& Jermy, B. Rabindran. Fabricating hierarchical ZSM-5 to induct long chain antioxidant coenzyme Q10 for biomedical application. Journal of Saudi Chemical Society. 2019. Vol. 23, no. 4, pp.461-476.
https://search.emarefa.net/detail/BIM-893489
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 475-476
Record ID
BIM-893489