Square wave voltammetric and computational study of thyroxine-thiourea interaction
Other Title(s)
دراسة فولتامتري الموجة المربعة و حاسوبية للتذاخل ما بين الثايروكسين والثايويوريا
Joint Authors
Abd al-Wahhab, Haytham A.
Sulayman, Sad Allah T.
Abd al-Fattah, Marwah N.
Source
Publisher
University of Mosul College of Science
Publication Date
2019-04-30
Country of Publication
Iraq
No. of Pages
9
Main Subjects
Topics
English Abstract
The voltammetric behavior of Thyroxine (T4) was studied using square wave voltammetry in phosphate buffer solution at (pH 7.0) as supporting electrolyte.
Thyroxine gives two well-defined reduction peaks at Ep1 (-0.359) volt and Ep2 (-1.01) volt versus the reference electrode (Ag/AgCl/Sat.KCl).
The calibration curve is linear within a two range of concentration, first is (1.996x10-7 - 19.61x10-7)M with the R2 equal to (0.999) and (0.9963) for Ep1 and Ep2 respectively, and second (0.996x10-6 - 11.857x10-6) M with the R2 equal to (0.9819) and (0.9848) for Ep1 and Ep2 respectively.
The Gibb`s free energy (ΔG), enthalpy (ΔH) and entropy (ΔS) changes of temperature dependent on (K) were calculated using Van`t Hoff equation for Thyroxine and Thiourea binding.
The molecular docking between Thyroxine and Thioureahas been studied, and the results indicates thatthe interaction between T4 and TU was mainly hydrogen bonding and van der Waal`s interaction.
Data Type
Conference Papers
Record ID
BIM-895025
American Psychological Association (APA)
Abd al-Fattah, Marwah N.& Sulayman, Sad Allah T.& Abd al-Wahhab, Haytham A.. 2019-04-30. Square wave voltammetric and computational study of thyroxine-thiourea interaction. Growing Chemistry Science and its Application (3 : 2019 : Banghazi, Libya). . Vol. 28, no. 2 (Special issue) (2019), pp.175-183.Mosul Iraq : University of Mosul College of Science.
https://search.emarefa.net/detail/BIM-895025
Modern Language Association (MLA)
Abd al-Fattah, Marwah N.…[et al.]. Square wave voltammetric and computational study of thyroxine-thiourea interaction. . Mosul Iraq : University of Mosul College of Science. 2019-04-30.
https://search.emarefa.net/detail/BIM-895025
American Medical Association (AMA)
Abd al-Fattah, Marwah N.& Sulayman, Sad Allah T.& Abd al-Wahhab, Haytham A.. Square wave voltammetric and computational study of thyroxine-thiourea interaction. . Growing Chemistry Science and its Application (3 : 2019 : Banghazi, Libya).
https://search.emarefa.net/detail/BIM-895025
