Evaluation of antioxidant and anticancer activities of chemical constituents of the Saururus chinensis root extracts
Joint Authors
Ahamid, Anis
Kumar, Radhakrishnan Surendra
Id Allah, Akbar
Arif, Ibrahim Abd al-Wahid
al-Aklabi, Abd Allah
Source
Saudi Journal of Biological Sciences
Issue
Vol. 25, Issue 7 (30 Nov. 2018), pp.1387-1392, 6 p.
Publisher
Publication Date
2018-11-30
Country of Publication
Saudi Arabia
No. of Pages
6
Main Subjects
Topics
Abstract EN
Evaluation of antioxidant and anticancer activities were screened by various Saururus chinensis root extracts.
Four solvents (ethyl acetate, methanol, ethanol, and water) extracts were investigated for their total flavonoids, phenol contents and their antioxidant activity of DPPH (2,2-diphenyl-1-picrylhydrazyl), NO (nitric oxide), H2O2 (hydrogen peroxide), ABTS 2,20-azino-bi s(3-ethylbenzothiazoline-6-sulfonicacid)diammonium assays, FRAP (ferric reducing ability of plasma) assays and anticancer activity.
The total phenolic and flavonoid content of extracts were determined by using FC (Folin–Ciocalteu) and AlCl3 colorimetric assay method.
Total flavonoid content in these plants ranged from 24.7 to 72.1 mg g 1 and amount of free phenolic compounds was between 11.2 and 67.1 mg g 1 extract.
The all extracts have significant levels of phenolics and flavonoids content.
Anticancer activity was screened for MCF-7 breast cancer cell line.
Ethanol extract shows significant of antioxidant activity and water extract shows significant of anticancer activity compared with standard (BHT) butylated hydroxy toluene.
These ethanol and water extracts could be considered as a natural source for using antioxidant, and anticancer agents compared to commercial available synthetic drugs.
American Psychological Association (APA)
al-Aklabi, Abd Allah& Arif, Ibrahim Abd al-Wahid& Ahamid, Anis& Kumar, Radhakrishnan Surendra& Id Allah, Akbar. 2018. Evaluation of antioxidant and anticancer activities of chemical constituents of the Saururus chinensis root extracts. Saudi Journal of Biological Sciences،Vol. 25, no. 7, pp.1387-1392.
https://search.emarefa.net/detail/BIM-896761
Modern Language Association (MLA)
al-Aklabi, Abd Allah…[et al.]. Evaluation of antioxidant and anticancer activities of chemical constituents of the Saururus chinensis root extracts. Saudi Journal of Biological Sciences Vol. 25, no. 7 (Nov. 2018), pp.1387-1392.
https://search.emarefa.net/detail/BIM-896761
American Medical Association (AMA)
al-Aklabi, Abd Allah& Arif, Ibrahim Abd al-Wahid& Ahamid, Anis& Kumar, Radhakrishnan Surendra& Id Allah, Akbar. Evaluation of antioxidant and anticancer activities of chemical constituents of the Saururus chinensis root extracts. Saudi Journal of Biological Sciences. 2018. Vol. 25, no. 7, pp.1387-1392.
https://search.emarefa.net/detail/BIM-896761
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 1392
Record ID
BIM-896761