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Fluorescence assessment for the efficacy of solid tumour treatment using photodynamic therapy modality
Joint Authors
al-Balah, Usamah Fikri
Ali, Huda E.
Mursi, Muna E.
Badr, Yahya Abd al-Hamid
al-Rubi, Mahmud N.
Source
Arab Journal of Nuclear Sciences and Applications
Issue
Vol. 51, Issue 1 (31 Jan. 2018), pp.135-141, 7 p.
Publisher
The Egyptian Society of Nuclear Science and Applications
Publication Date
2018-01-31
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Topics
Abstract EN
Photodynamic therapy is an approved therapeutic modality for treatment of a variety of specific types of cancerous diseases.
In the present study PDT was used as a treatment of induced solid tumour at the hind limp of albino mice using photo sensitizer 5,10,15,20-Tetra(4-methoxyphenyl)porphyrin(TMP) 0.5 mg/kg and irradiated with diode laser at wavelength 650 nm (irradiance 707 mW/cm2).
45 female Swiss albino mice were divided into three groups’ normal group, malignant group and treated group.
Assessment was done by detecting fluorescence emission spectra and spectral line using fluorimeter and Raman spectroscopy technique.
Obtained fluorescence of tryptophan and tyrosine gave higher intensity for tumor rather than normal and reduced after treatment to almost near normal spectra
American Psychological Association (APA)
Ali, Huda E.& Badr, Yahya Abd al-Hamid& Mursi, Muna E.& al-Balah, Usamah Fikri& al-Rubi, Mahmud N.. 2018. Fluorescence assessment for the efficacy of solid tumour treatment using photodynamic therapy modality. Arab Journal of Nuclear Sciences and Applications،Vol. 51, no. 1, pp.135-141.
https://search.emarefa.net/detail/BIM-898824
Modern Language Association (MLA)
Ali, Huda E.…[et al.]. Fluorescence assessment for the efficacy of solid tumour treatment using photodynamic therapy modality. Arab Journal of Nuclear Sciences and Applications Vol. 51, no. 1 (Jan. 2018), pp.135-141.
https://search.emarefa.net/detail/BIM-898824
American Medical Association (AMA)
Ali, Huda E.& Badr, Yahya Abd al-Hamid& Mursi, Muna E.& al-Balah, Usamah Fikri& al-Rubi, Mahmud N.. Fluorescence assessment for the efficacy of solid tumour treatment using photodynamic therapy modality. Arab Journal of Nuclear Sciences and Applications. 2018. Vol. 51, no. 1, pp.135-141.
https://search.emarefa.net/detail/BIM-898824
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 140-141
Record ID
BIM-898824