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Tamoxifen Effects on the lipid profile in premenopausal women with Breast cancer : a follow up study
Other Title(s)
تأثير التاموكسفين على مستوى الدهون في النساء ما قبل سن اليأس المصابات بسرطان الثدي
Joint Authors
al-Saidi, Wasan Kharibit Jasim
Ali, Zaynab Abbas Muhammad
Husayn, Dilan Zakariyya
al-Naqqash, Munawwir Abd al-Ilah
Source
Journal of the Faculty of Medicine Baghdad
Issue
Vol. 60, Issue 3 (30 Sep. 2018), pp.141-144, 4 p.
Publisher
University of Baghdad Faculty of Medicine
Publication Date
2018-09-30
Country of Publication
Iraq
No. of Pages
4
Main Subjects
Abstract EN
Background : Breast cancer composed of several biologic subtypes that have response to hormonal therapy.
Tamoxifen is hormonal therapy with tissue- pecific antagonistic or agonist effects, the latter being responsible for multiple effects on lipid metabolism in women .
Objective : This study was designed to determine the impact of Tamoxifen on the serum lipid profile in breast cancer women.
Patients and methods : Prospective observation cohort study conducted at Oncology Teaching Hospital, Medical city complx.starting from October 2015 to October 2016.
A total number of 40 premenopausal women with breast cancer were enrolled in this study according to inclusion criteria .
Patients were followed for three months by the measurements TC, TG, HDL – cholesterol and BMI .
Results : At the end of third months of hormonal therapy, Tamoxifen showed a significant decrease in TG, VLDL (p< 0.001 for both).
On the other side HDL and BMI showed significant increase over three months duration , (p = 0.001 and 0.006, respectively) .
Conclusion : Beneficial alterations of lipid profiles were seen in pre-menopausal breast cancer patients treated with Tamoxifen.
American Psychological Association (APA)
Ali, Zaynab Abbas Muhammad& al-Saidi, Wasan Kharibit Jasim& Husayn, Dilan Zakariyya& al-Naqqash, Munawwir Abd al-Ilah. 2018. Tamoxifen Effects on the lipid profile in premenopausal women with Breast cancer : a follow up study. Journal of the Faculty of Medicine Baghdad،Vol. 60, no. 3, pp.141-144.
https://search.emarefa.net/detail/BIM-899528
Modern Language Association (MLA)
Ali, Zaynab Abbas Muhammad…[et al.]. Tamoxifen Effects on the lipid profile in premenopausal women with Breast cancer : a follow up study. Journal of the Faculty of Medicine Baghdad Vol. 60, no. 3 (2018), pp.141-144.
https://search.emarefa.net/detail/BIM-899528
American Medical Association (AMA)
Ali, Zaynab Abbas Muhammad& al-Saidi, Wasan Kharibit Jasim& Husayn, Dilan Zakariyya& al-Naqqash, Munawwir Abd al-Ilah. Tamoxifen Effects on the lipid profile in premenopausal women with Breast cancer : a follow up study. Journal of the Faculty of Medicine Baghdad. 2018. Vol. 60, no. 3, pp.141-144.
https://search.emarefa.net/detail/BIM-899528
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 143-144
Record ID
BIM-899528