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Evaluation and correlation of hepcidin-25 hormone, hemoglobin and packed cell volume of patients with β-thalassaemia intermedia before and after blood transfusion for iraqi children patients
Joint Authors
Sadun, Muhammad K.
Ali, Bushra H.
Source
Ibn al-Haitham Journal for Pure and Applied Science
Issue
Vol. 31, Issue 3 (31 Dec. 2018), pp.70-78, 9 p.
Publisher
University of Baghdad College of Education for Pure Science / Ibn al-Haitham
Publication Date
2018-12-31
Country of Publication
Iraq
No. of Pages
9
Main Subjects
Abstract EN
P-thalassaemia consists of 3 chief forms: thalassaemia primary (other called "cooley's Anaemia" or "Mediterranean durability Anaemia”), thalassaemia intermedia or thalassaemia minor also frequent termed "P-thalassaenna carrier", "P-thalassaemia trait" however, "heterozygous P-thalassaemia".
separately from the rare magisterial forms, problem along P- thalassaemia essential are komozygotes or made heterozygotes because B° and B~ genes, problem including thalassaemia intermedia are typically homozygotes and compound heterozygotes then subjected with thalassaemia minor are broadly heterozygotes.
In this study, we take eighty humans the age about them had been mean=SD (9.68=2.08).
40 patients along P-thalassaemia intermedia, then 40 healthy people as much control, extraction gore 5ml from thalassaemia's patients before gore transfusion then afterwards take the blood by way of three days.
The samples we instituted are 120.
forty samples before blood transfusion.
40 samples after gore transfusion then 40 control samples.
Then we separated every pattern of twin's tubes.
Amplify blood attention about P-thalassaenua intermedia patient since blood advancement due according to minimize degree regarding hepcidin-25 further than its instruction was once shown up iron focus meanly affect through hepcidin-25 level, therefore so hepcidin-25 used to be surprisingly significant exchange in P- thalassaemia intermedia affected person afterwards blood advancement yet so much conduct to iron overload.
So we conclude low level of Hemoglobin before and after blood transfusion due to decrease or absent formation of P-globin that because gene disorder, and conclude correlation between kepcidin hormone with Hb and PCV.
The aim of this study is to evaluate hepcidin-25 levels, hemoglobm [Hb] and packed cell volume [PCV] before and after blood transfusion, then correlation of hepcidin-25 hormone with [Hb] and [PCV] of children patients with P-thalassaemia intermedia.
American Psychological Association (APA)
Sadun, Muhammad K.& Ali, Bushra H.. 2018. Evaluation and correlation of hepcidin-25 hormone, hemoglobin and packed cell volume of patients with β-thalassaemia intermedia before and after blood transfusion for iraqi children patients. Ibn al-Haitham Journal for Pure and Applied Science،Vol. 31, no. 3, pp.70-78.
https://search.emarefa.net/detail/BIM-900651
Modern Language Association (MLA)
Sadun, Muhammad K.& Ali, Bushra H.. Evaluation and correlation of hepcidin-25 hormone, hemoglobin and packed cell volume of patients with β-thalassaemia intermedia before and after blood transfusion for iraqi children patients. Ibn al-Haitham Journal for Pure and Applied Science Vol. 31, no. 3 (2018), pp.70-78.
https://search.emarefa.net/detail/BIM-900651
American Medical Association (AMA)
Sadun, Muhammad K.& Ali, Bushra H.. Evaluation and correlation of hepcidin-25 hormone, hemoglobin and packed cell volume of patients with β-thalassaemia intermedia before and after blood transfusion for iraqi children patients. Ibn al-Haitham Journal for Pure and Applied Science. 2018. Vol. 31, no. 3, pp.70-78.
https://search.emarefa.net/detail/BIM-900651
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 76-78
Record ID
BIM-900651