Synthesis and evaluation the activity of 1,3,4-thiadiazole derivatives as antibacterial agent against uncommon bacteria causes of urinary tract infections
Other Title(s)
تصنيع و تقييم فعالية مشتقات 1,3,4-Thiadiazole كعامل مضاد للبكتريا غير الشائعة المسببة لالتهابات المسالك البولية
Joint Authors
Dahham, Shayma N.
Abd al-Wahhab, Marwah H.
Mahmud, Asma E.
Akram, Ivon
Source
Publisher
University of Mosul College of Science
Publication Date
2018-10-31
Country of Publication
Iraq
No. of Pages
13
Main Subjects
English Abstract
Schiff base compound 5-(benzylideneamino)-1,3,4-thiadiazole-2-thiol was prepared from condensation reaction of 2-amino-5-mercapto-1,3,4-thiadiazole with benzaldehyde.
New Schiff bases react with copper (II), Ferric (III), Cobalt (II) and Zinc (II) to form four complexes.
The Schiff base complexes were identification by using FTIR and UV-VIS.
The antibacterial activity of complexes (Copper (II) LM1, Ferric (III) LM2, Cobalt (II) LM3 and Zinc (II) LM4 complexes) were studied against Kocuria kristinae, Alloiococcus otiti and Aerococcus urinae as a model of Gram positive, Pseudomonas stutzeri, Ochrobactrum anthropic and Pantoea agglomerans as a model of Gram negative to determine the activity of synthesized complexes.
Identification of these uncommon bacteria that isolated from urinary tract infection confirmed by using VITEK2 compact system.
Several antibiotics have been chosen to investigate the ability of these isolates to resist the conventional antibiotic.
The results showed higher activity of the new compounds relative to the chosen antibiotics.
Data Type
Conference Papers
Record ID
BIM-902263
American Psychological Association (APA)
Dahham, Shayma N.& Abd al-Wahhab, Marwah H.& Mahmud, Asma E.& Akram, Ivon. 2018-10-31. Synthesis and evaluation the activity of 1,3,4-thiadiazole derivatives as antibacterial agent against uncommon bacteria causes of urinary tract infections. Conference of Biology (3rd : 2018 : Kufa, Iraq). . Vol. 27, no. 5 (Special issue) (2018), pp.58-70.Mosul Iraq : University of Mosul College of Science.
https://search.emarefa.net/detail/BIM-902263
Modern Language Association (MLA)
Dahham, Shayma N.…[et al.]. Synthesis and evaluation the activity of 1,3,4-thiadiazole derivatives as antibacterial agent against uncommon bacteria causes of urinary tract infections. . Mosul Iraq : University of Mosul College of Science. 2018-10-31.
https://search.emarefa.net/detail/BIM-902263
American Medical Association (AMA)
Dahham, Shayma N.& Abd al-Wahhab, Marwah H.& Mahmud, Asma E.& Akram, Ivon. Synthesis and evaluation the activity of 1,3,4-thiadiazole derivatives as antibacterial agent against uncommon bacteria causes of urinary tract infections. . Conference of Biology (3rd : 2018 : Kufa, Iraq).
https://search.emarefa.net/detail/BIM-902263
