Comparison of two forms of dinoprostone : propess and prostin for induction of labor
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Background: Induction of labor (IOL) aims to achieve a successful vaginal delivery.
Dinoprostone is a synthetic prostaglandin (PGE2) which works on the connective tissue stroma of the cervix and makes it favorable for normal labor.
Objective: To compare the two variants of PGE2: intra-vaginal dinoprostone vaginal suppository (Prostin E2) and 24 hours controlled-release vaginal dinoprostone pessary (Propess) for successful normal vaginal delivery.
Setting: Obstetrics and Gynecology Department, Bahrain Defence Force Hospital, Bahrain.
Design: A Retrospective Study.
Method: This study included all pregnant women who had induction of labor from January 2018 to June 2018.
A total of 322 women with a singleton pregnancy, fetal cephalic presentation and bishop score ≤4 were admitted for induction of labor.
Fifty-eight (18%) patients received 24-hours 10 mg controlled-release Propess and 264 (81.9%) received repeated doses of 2 mg Prostin E2 vaginal tablets.
Result: A high incidence of cesarean delivery in the Propess group 20/58 (34.5%) compared to 45/264 (17%) in the Prostin group was found, P-value of 0.002.
There was no difference in the incidence of hyperstimulation, need for oxytocin or fetal distress in labor.
Shorter induction-todelivery interval was obtained with Propess, 19 hours compared to 23.5 hours for Prostin E2, but the difference was not statistically significant.
Data was analyzed using StatsDirect software, P-value of less than 0.05 was considered statistically significant.
Conclusion: IOL with slow release dinoprostone is associated with increased cesarean section rate compared to Prostin.
American Psychological Association (APA)
Baha, Iman& Khalid, Layla& Duyub, Nawal. 2019. Comparison of two forms of dinoprostone : propess and prostin for induction of labor. Bahrain Medical Bulletin،Vol. 41, no. 4, pp.226-229.
Modern Language Association (MLA)
Baha, Iman…[et al.]. Comparison of two forms of dinoprostone : propess and prostin for induction of labor. Bahrain Medical Bulletin Vol. 41, no. 4 (Dec. 2019), pp.226-229.
American Medical Association (AMA)
Baha, Iman& Khalid, Layla& Duyub, Nawal. Comparison of two forms of dinoprostone : propess and prostin for induction of labor. Bahrain Medical Bulletin. 2019. Vol. 41, no. 4, pp.226-229.
Includes bibliographical references : p. 229
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