Comparison of two forms of dinoprostone : propess and prostin for induction of labor

Joint Authors

Duyub, Nawal
Baha, Iman
Khalid, Layla

Source

Bahrain Medical Bulletin

Issue

Vol. 41, Issue 4 (31 Dec. 2019), pp.226-229, 4 p.

Publisher

King Hamad University Hospital

Publication Date

2019-12-31

Country of Publication

Bahrain

No. of Pages

4

Main Topic

Medicine

Topics

Abstract EN

Background: Induction of labor (IOL) aims to achieve a successful vaginal delivery.

Dinoprostone is a synthetic prostaglandin (PGE2) which works on the connective tissue stroma of the cervix and makes it favorable for normal labor.

Objective: To compare the two variants of PGE2: intra-vaginal dinoprostone vaginal suppository (Prostin E2) and 24 hours controlled-release vaginal dinoprostone pessary (Propess) for successful normal vaginal delivery.

Setting: Obstetrics and Gynecology Department, Bahrain Defence Force Hospital, Bahrain.

Design: A Retrospective Study.

Method: This study included all pregnant women who had induction of labor from January 2018 to June 2018.

A total of 322 women with a singleton pregnancy, fetal cephalic presentation and bishop score ≤4 were admitted for induction of labor.

Fifty-eight (18%) patients received 24-hours 10 mg controlled-release Propess and 264 (81.9%) received repeated doses of 2 mg Prostin E2 vaginal tablets.

Result: A high incidence of cesarean delivery in the Propess group 20/58 (34.5%) compared to 45/264 (17%) in the Prostin group was found, P-value of 0.002.

There was no difference in the incidence of hyperstimulation, need for oxytocin or fetal distress in labor.

Shorter induction-todelivery interval was obtained with Propess, 19 hours compared to 23.5 hours for Prostin E2, but the difference was not statistically significant.

Data was analyzed using StatsDirect software, P-value of less than 0.05 was considered statistically significant.

Conclusion: IOL with slow release dinoprostone is associated with increased cesarean section rate compared to Prostin.

American Psychological Association (APA)

Baha, Iman& Khalid, Layla& Duyub, Nawal. 2019. Comparison of two forms of dinoprostone : propess and prostin for induction of labor. Bahrain Medical Bulletin،Vol. 41, no. 4, pp.226-229.
https://search.emarefa.net/detail/BIM-910491

Modern Language Association (MLA)

Baha, Iman…[et al.]. Comparison of two forms of dinoprostone : propess and prostin for induction of labor. Bahrain Medical Bulletin Vol. 41, no. 4 (Dec. 2019), pp.226-229.
https://search.emarefa.net/detail/BIM-910491

American Medical Association (AMA)

Baha, Iman& Khalid, Layla& Duyub, Nawal. Comparison of two forms of dinoprostone : propess and prostin for induction of labor. Bahrain Medical Bulletin. 2019. Vol. 41, no. 4, pp.226-229.
https://search.emarefa.net/detail/BIM-910491

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references : p. 229

Record ID

BIM-910491