معالجة أورام الخلايا المنتشة الناكسة : دراسة مقارنة لطرائق العلاج المتبعة عالميا
Other Title(s)
Treatment of rlapsed germ cen tumors : a comparative study of internationally-followed therapy methods
Author
Source
Issue
Vol. 33, Issue 2 (31 Dec. 2017), pp.63-73, 11 p.
Publisher
Publication Date
2017-12-31
Country of Publication
Syria
No. of Pages
11
Main Subjects
Abstract EN
The principd of high-dose chemotherapy (HDCT) with autologous stem cell transplantation has been studied in both salvage and primary therapy setting in advanced and met.
germ cell tumor (GCT).
Previously the studies reported significant treatment-related mortality, introduction of peripheral blood stem cell transplantation, recombinant growth factors and better supportive care with G-CSF wich have decreased this toxicity and mortality.
High-dose chemotherapy (HDCT) is potentially curative in the second- and third-line therapy for patients with advanced germ cell tumor Two to three cycles of high-dose carboplatin and etoposide is the standard of HDCT, given with or without additional agents including ifosfamide, and paclitaxel.
Three large randomized Phase III trials have failed to show a benefit of HDCT over conventional-dose chemotherapy (CDCT) in the first-line treatment of patients with advanced GCT.
To date, the routine usage of HDCT has been reserved only for the salvage setting.
Patients with refractory or relapsed disease.
despite treatment under high-dose protocols, are generally considered to have incurable disease.
additional therapy is provided with palliative intent
American Psychological Association (APA)
خازم، نسرين رزق. 2017. معالجة أورام الخلايا المنتشة الناكسة : دراسة مقارنة لطرائق العلاج المتبعة عالميا. مجلة جامعة دمشق للعلوم الطبية،مج. 33، ع. 2، ص ص. 63-73.
https://search.emarefa.net/detail/BIM-930354
Modern Language Association (MLA)
خازم، نسرين رزق. معالجة أورام الخلايا المنتشة الناكسة : دراسة مقارنة لطرائق العلاج المتبعة عالميا. مجلة جامعة دمشق للعلوم الطبية مج. 33، ع. 2 (2017)، ص ص. 63-73.
https://search.emarefa.net/detail/BIM-930354
American Medical Association (AMA)
خازم، نسرين رزق. معالجة أورام الخلايا المنتشة الناكسة : دراسة مقارنة لطرائق العلاج المتبعة عالميا. مجلة جامعة دمشق للعلوم الطبية. 2017. مج. 33، ع. 2، ص ص. 63-73.
https://search.emarefa.net/detail/BIM-930354
Data Type
Journal Articles
Language
Arabic
Notes
يتضمن مراجع ببليوجرافية : ص. 72-73
Record ID
BIM-930354