Study the protective effect of radish (Raphanus sativus) seeds extract against harmful effects of sodium nitrite on some physiological and histological parameters in male rabbits
Other Title(s)
دراسة التأثير الواقي لمستخلص بذور الفجل (Raphanus sativus) ضد التأثيرات الضارة لنتريت الصوديوم على بعض المؤشرات الفسلجية و النسجية في ذكور الأرانب
Joint Authors
Habah, Mukhtar Khamis
Ali, Aliyah Husayn
Abd al-Aziz, Lina A.
Source
Iraqi Journal of Biotechnology
Issue
Vol. 14, Issue 2 (31 Dec. 2015), pp.59-78, 20 p.
Publisher
University of Baghdad Genetic Engineering and Biotechnology for Postgraduate Studies
Publication Date
2015-12-31
Country of Publication
Iraq
No. of Pages
20
Main Subjects
Abstract EN
The aim of this study is to investigate the protective effect of Radish (Raphanus sativus) seeds ethanolic extract 70% against harmful effects of sodium nitrite (NaNOR2R)R Ron some physiological and histological parameters of liver and kidney in male rabbits.R R Twenty five adult male rabbits were used in this study, divided into five groups (five rabbits in each group) and intubated daily for 30 days.
Group T1: intubated orally 20 mg/kg NaNOR2R, Group T2: intubated orally 20 mg/kg NaNOR2R + 50 mg/kg of ethanolic extract from Raphanus sativus seeds, Group T3: intubated orally 20 mg/kg NaNOR2R + 100 mg/kg of ethanolic extract from Raphanus sativus seeds, Group T4: intubated orally 20 mg/kg NaNOR2R + 200 mg/kg of ethanolic extract from Raphanus sativus seeds as well as Group C: control intubated orally distilled water.
In rabbits intubated with NaNOR2R, the results showed that there were increasing in the level of liver enzymes (AST, ALT and ALP) and kidney functions parameters (Uric acid and Creatinine) in comparison with normal rabbits (control).
In rabbits intubated with NaNOR2R + 50,100,200 mg/kg of ethanolic extract of Raphanus Sativus seeds, this study explained that there were decreasing in the level of liver enzymes (AST, ALT and ALP) and kidney functions parameters (uric acid and creatinine) in comparison with rabbits intubated with NaNOR2 Ronly.
Histological sections of liver and kidney of sodium nitrite treated group revealed congestion of blood vessels, infiltration, fatty degeneration, While histological examination findings of sodium nitrite + Raphanus sativus seeds extract treated groups revealed healing of liver and kidney tissue.
In conclusion according to results obtained from this study that alcoholic extract of Raphanus sativus seeds in dose (50,100,200 mg/kg) have protective role against harmful effect of sodium nitrite on liver and kidney in male rabbits
American Psychological Association (APA)
Abd al-Aziz, Lina A.& Ali, Aliyah Husayn& Habah, Mukhtar Khamis. 2015. Study the protective effect of radish (Raphanus sativus) seeds extract against harmful effects of sodium nitrite on some physiological and histological parameters in male rabbits. Iraqi Journal of Biotechnology،Vol. 14, no. 2, pp.59-78.
https://search.emarefa.net/detail/BIM-955913
Modern Language Association (MLA)
Abd al-Aziz, Lina A.…[et al.]. Study the protective effect of radish (Raphanus sativus) seeds extract against harmful effects of sodium nitrite on some physiological and histological parameters in male rabbits. Iraqi Journal of Biotechnology Vol. 14, no. 2 (2015), pp.59-78.
https://search.emarefa.net/detail/BIM-955913
American Medical Association (AMA)
Abd al-Aziz, Lina A.& Ali, Aliyah Husayn& Habah, Mukhtar Khamis. Study the protective effect of radish (Raphanus sativus) seeds extract against harmful effects of sodium nitrite on some physiological and histological parameters in male rabbits. Iraqi Journal of Biotechnology. 2015. Vol. 14, no. 2, pp.59-78.
https://search.emarefa.net/detail/BIM-955913
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 75-78
Record ID
BIM-955913