Evaluation of lactoferrin immunomodulatory effect on the immune response of broiler chickens
Other Title(s)
تقييم تاثير مستخلص اللاكتوفيريه كمعدل مناعي علي الاستجابة المناعية فى دجاج التسمين
Joint Authors
Sulayman, Rafiq Tawfiq Muhammad
Anani, M. E.
Hubayshi, Asma Abd Allah
al-Jamal, Abd al-Azim Muhammad
al-Sisi, Ashgan F.
Source
Suez Canal Veterinary Medicine Journal
Issue
Vol. 22, Issue 1 (30 Jun. 2017), pp.135-146, 12 p.
Publisher
Suez Canal University Faculty of Veterinary Medicine
Publication Date
2017-06-30
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
Immunomodulators are substances that able to regulate or modulate immune responses.
In order to investigate the lactoferrin effect on the immune system of broiler chickens, one hundred twenty (1-dayold) chicks of both sexes were randomly allocated into 2 dietary groups (60 chicks/group), group1 (G1): chicks were offered basal diets and kept as control group, group2 (G2): Chicks were offered basal diets supplemented with lactoferrin (250mg/kg diet for 6 weeks).
Evaluating the effects of dietary supplementation with lactoferrin on growth performance of broiler chicks, humeral immunity by measuring antibody titer against Newcastle (ND) and Avian influenza (AIV)vaccine, and on innate immunity by measuring some functions of peripheral blood monocytes (PBM) as phagocytic activity, fungicidal activity, nitric oxide (NO) production and reactive oxygen species (ROS) production by tetrazolium reduction test.
To study antibacterial effect of lactoferrin, challenge test was carried out using virulent E.
coli strain .The results revealed that, lactoferrin improve growth performance and could stimulate the humeral immunity by increasing the antibody titer aginst ND and AIV vaccine .Also lactoferrin could enhance the innate immunity by significant increasing of phagocytic and Fungicidal activities of PBM and its production of ROS and NO.
Lactoferrin have the ability to protect broiler chickens from virulent agents as E.
coli.
Therefore, lactoferrin may be used as immunostimulant, growth promoters and antibacterial agent in broiler chickens.
American Psychological Association (APA)
Anani, M. E.& al-Jamal, Abd al-Azim Muhammad& Sulayman, Rafiq Tawfiq Muhammad& al-Sisi, Ashgan F.& Hubayshi, Asma Abd Allah. 2017. Evaluation of lactoferrin immunomodulatory effect on the immune response of broiler chickens. Suez Canal Veterinary Medicine Journal،Vol. 22, no. 1, pp.135-146.
https://search.emarefa.net/detail/BIM-960729
Modern Language Association (MLA)
Anani, M. E.…[et al.]. Evaluation of lactoferrin immunomodulatory effect on the immune response of broiler chickens. Suez Canal Veterinary Medicine Journal Vol. 22, no. 1 (2017), pp.135-146.
https://search.emarefa.net/detail/BIM-960729
American Medical Association (AMA)
Anani, M. E.& al-Jamal, Abd al-Azim Muhammad& Sulayman, Rafiq Tawfiq Muhammad& al-Sisi, Ashgan F.& Hubayshi, Asma Abd Allah. Evaluation of lactoferrin immunomodulatory effect on the immune response of broiler chickens. Suez Canal Veterinary Medicine Journal. 2017. Vol. 22, no. 1, pp.135-146.
https://search.emarefa.net/detail/BIM-960729
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p143-145
Record ID
BIM-960729