The Comparison of Teen Clubs vs. Standard Care on Treatment Outcomes for Adolescents on Antiretroviral Therapy in Windhoek, Namibia

Joint Authors

Munyayi, Farai K.
van Wyk, Brian E.

Source

AIDS Research and Treatment

Issue

Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-9, 9 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2020-10-27

Country of Publication

Egypt

No. of Pages

9

Main Topic

Diseases
Medicine

Abstract EN

Adolescents living with HIV (ALHIV) are challenged to adhere to antiretroviral therapy (ART) and achieve and maintain virologic suppression.

Group-based adherence support interventions, such as adherence clubs, have been shown to improve long-term adherence in ART patients.

The teen club intervention was introduced in 2010 in Namibia to improve treatment outcomes for ALHIV by providing adherence support in a peer-group environment.

Adolescents who have completed the full HIV disclosure process can voluntarily join the teen clubs.

The current study compared treatment outcomes of ALHIV receiving ART at a specialized paediatric HIV clinic between 1 July 2015 and 30 June 2017 in Windhoek, Namibia.

Methods.

A retrospective cohort analysis was conducted on routine patient data extracted from the electronic Patient Monitoring System, individual Patient Care Booklets, and teen club attendance registers.

A sample of 385 adolescents were analysed: 78 in teen clubs and 307 in standard care.

Virologic suppression was determined at 6, 12, and 18 months from study start date, and compared by model of care, age, sex, disclosure status, and ART regimen.

Comparisons between adolescents in teen clubs and those receiving standard care were performed using the chi-square test, and risk ratios were calculated to analyze differences in ART adherence and virologic suppression.

Results.

The average clinician-measured ART adherence was 89% good, 6% fair, and 5% poor amongst all adolescents, with no difference between teen club members and adolescents in standard care (p = 0.277) at 3 months.

Virologic suppression over the 2-year observation period was 87% (68% fully suppressed <40 copies/ml and 19% suppressed between 40–999 copies/ml), with no difference between teen club members and those in standard care.

However, there were statistically significant differences in virologic suppression levels between the younger (10–14 years) adolescents and older (15–19 years) adolescents at 6 months (p = 0.015) and at 12 months (p = 0.021) and between adolescents on first-line and second-line ART regimen at 6 months (p = 0.012), 12 months (p = 0.004), and 18 months (p = 0.005).

Conclusion.

The teen club model delivering psychosocial support only did not improve adherence and virologic suppression levels for adolescents in a specialized paediatric ART clinic, neither were they inferior to standard care.

Considering the limitations of this study, teen clubs may still hold potential for improving adherence and virologic suppression levels for older adolescents, and more robust research on adherence interventions for adolescents with higher methodological quality is required.

American Psychological Association (APA)

Munyayi, Farai K.& van Wyk, Brian E.. 2020. The Comparison of Teen Clubs vs. Standard Care on Treatment Outcomes for Adolescents on Antiretroviral Therapy in Windhoek, Namibia. AIDS Research and Treatment،Vol. 2020, no. 2020, pp.1-9.
https://search.emarefa.net/detail/BIM-986238

Modern Language Association (MLA)

Munyayi, Farai K.& van Wyk, Brian E.. The Comparison of Teen Clubs vs. Standard Care on Treatment Outcomes for Adolescents on Antiretroviral Therapy in Windhoek, Namibia. AIDS Research and Treatment No. 2020 (2020), pp.1-9.
https://search.emarefa.net/detail/BIM-986238

American Medical Association (AMA)

Munyayi, Farai K.& van Wyk, Brian E.. The Comparison of Teen Clubs vs. Standard Care on Treatment Outcomes for Adolescents on Antiretroviral Therapy in Windhoek, Namibia. AIDS Research and Treatment. 2020. Vol. 2020, no. 2020, pp.1-9.
https://search.emarefa.net/detail/BIM-986238

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-986238