Nutrition before and during Surgery and the Inflammatory Response of the Heart: A Randomized Controlled Trial
المؤلفون المشاركون
van Leeuwen, P. A. M.
Niessen, Hans M.
Wisselink, Willem
Visser, Marlieke
Kok, Wouter E. M.
Cocchieri, Riccardo
de Mol, Bas A. J. M.
المصدر
Journal of Nutrition and Metabolism
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-07-29
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Major surgery induces a long fasting time and provokes an inflammatory response which increases the risk of infections.
Nutrition given before and during surgery can avoid fasting and has been shown to increase the arginine/asymmetric dimetlhylarginine ratio, a marker of nitric oxide availability, in cardiac tissue and increased concentrations of branched chain amino acids in blood plasma.
However, the effect of this new nutritional strategy on organ inflammatory response is unknown.
Therefore, we studied the effect of nutrition before and during cardiac surgery on myocardial inflammatory response.
In this trial, 32 patients were randomised between enteral, parenteral, and no nutrition supplementation (control) from 2 days before, during, up to 2 days after coronary artery bypass grafting.
Both solutions included proteins or amino acids, glucose, vitamins, and minerals.
Myocardial atrial tissue was sampled before and after revascularization and was analysed immunohistochemically, subdivided into cardiomyocytic, fatty, and fibrotic areas.
Inflammatory cells, especially leukocytes, were present in cardiac tissue in all study groups.
No significant differences were found in the myocardial inflammatory response between the enteral, parenteral, and control groups.
In conclusion, nutrition given before and during surgery neither stimulates nor diminishes the myocardial inflammatory response in patients undergoing coronary artery bypass grafting.
The trial was registered in Netherlands Trial Register (NTR): NTR2183.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Visser, Marlieke& Niessen, Hans M.& Kok, Wouter E. M.& Cocchieri, Riccardo& Wisselink, Willem& van Leeuwen, P. A. M.…[et al.]. 2015. Nutrition before and during Surgery and the Inflammatory Response of the Heart: A Randomized Controlled Trial. Journal of Nutrition and Metabolism،Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1069506
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Visser, Marlieke…[et al.]. Nutrition before and during Surgery and the Inflammatory Response of the Heart: A Randomized Controlled Trial. Journal of Nutrition and Metabolism No. 2015 (2015), pp.1-8.
https://search.emarefa.net/detail/BIM-1069506
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Visser, Marlieke& Niessen, Hans M.& Kok, Wouter E. M.& Cocchieri, Riccardo& Wisselink, Willem& van Leeuwen, P. A. M.…[et al.]. Nutrition before and during Surgery and the Inflammatory Response of the Heart: A Randomized Controlled Trial. Journal of Nutrition and Metabolism. 2015. Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1069506
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1069506
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر