Maternal Fructose Intake Induces Insulin Resistance and Oxidative Stress in Male, but Not Female, Offspring
المؤلفون المشاركون
Álvarez-Millán, Juan José
Rodríguez, Lourdes
Otero, Paola
Panadero, María I.
Rodrigo, Silvia
Bocos, Carlos
المصدر
Journal of Nutrition and Metabolism
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-02-11
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Objective.
Fructose intake from added sugars correlates with the epidemic rise in metabolic syndrome and cardiovascular diseases.
However, consumption of beverages containing fructose is allowed during gestation.
Recently, we found that an intake of fructose (10% wt/vol) throughout gestation produces an impaired fetal leptin signalling.
Therefore, we have investigated whether maternal fructose intake produces subsequent changes in their progeny.
Methods.
Blood samples from fed and 24 h fasted female and male 90-day-old rats born from fructose-fed, glucose-fed, or control mothers were used.
Results.
After fasting, HOMA-IR and ISI (estimates of insulin sensitivity) were worse in male descendents from fructose-fed mothers in comparison to the other two groups, and these findings were also accompanied by a higher leptinemia.
Interestingly, plasma AOPP and uricemia (oxidative stress markers) were augmented in male rats from fructose-fed mothers compared to the animals from control or glucose-fed mothers.
In contrast, female rats did not show any differences in leptinemia between the three groups.
Further, insulin sensitivity was significantly improved in fasted female rats from carbohydrate-fed mothers.
In addition, plasma AOPP levels tended to be diminished in female rats from carbohydrate-fed mothers.
Conclusion.
Maternal fructose intake induces insulin resistance, hyperleptinemia, and plasma oxidative stress in male, but not female, progeny.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Rodríguez, Lourdes& Otero, Paola& Panadero, María I.& Rodrigo, Silvia& Álvarez-Millán, Juan José& Bocos, Carlos. 2015. Maternal Fructose Intake Induces Insulin Resistance and Oxidative Stress in Male, but Not Female, Offspring. Journal of Nutrition and Metabolism،Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1069508
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Rodríguez, Lourdes…[et al.]. Maternal Fructose Intake Induces Insulin Resistance and Oxidative Stress in Male, but Not Female, Offspring. Journal of Nutrition and Metabolism No. 2015 (2015), pp.1-8.
https://search.emarefa.net/detail/BIM-1069508
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Rodríguez, Lourdes& Otero, Paola& Panadero, María I.& Rodrigo, Silvia& Álvarez-Millán, Juan José& Bocos, Carlos. Maternal Fructose Intake Induces Insulin Resistance and Oxidative Stress in Male, but Not Female, Offspring. Journal of Nutrition and Metabolism. 2015. Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1069508
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1069508
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر