Hyperuricemia in Children and Adolescents: Present Knowledge and Future Directions
المؤلف
المصدر
Journal of Nutrition and Metabolism
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-05-02
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Recent evidence suggests that hyperuricemia is an important condition in children and adolescents, particularly in association with noncommunicable diseases.
This review aims to summarize our current understanding of this condition in pediatric patients.
An analysis of serum uric acid reference values in a healthy population indicates that they increase gradually with age until adolescence, with differences between the sexes arising at about 12 years of age.
This information should be taken into consideration when defining hyperuricemia in studies.
Gout is extremely rare in children and adolescents, and most patients with gout have an underlying disease.
The major causes of hyperuricemia are chronic conditions, including Down syndrome, metabolic or genetic disease, and congenital heart disease, and acute conditions, including gastroenteritis, bronchial asthma (hypoxia), malignant disorders, and drug side effects.
The mechanisms underlying the associations between these diseases and hyperuricemia are discussed, together with recent genetic information.
Obesity is a major cause of hyperuricemia in otherwise healthy children and adolescents.
Obesity is often accompanied by metabolic syndrome; hyperuricemia in obese children and adolescents is associated with the components of metabolic syndrome and noncommunicable diseases, including hypertension, insulin resistance, dyslipidemia, and chronic kidney disease.
Finally, strategies for the treatment of hyperuricemia, including lifestyle intervention and drug administration, are presented.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Kubota, Masaru. 2019. Hyperuricemia in Children and Adolescents: Present Knowledge and Future Directions. Journal of Nutrition and Metabolism،Vol. 2019, no. 2019, pp.1-8.
https://search.emarefa.net/detail/BIM-1183605
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Kubota, Masaru. Hyperuricemia in Children and Adolescents: Present Knowledge and Future Directions. Journal of Nutrition and Metabolism No. 2019 (2019), pp.1-8.
https://search.emarefa.net/detail/BIM-1183605
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Kubota, Masaru. Hyperuricemia in Children and Adolescents: Present Knowledge and Future Directions. Journal of Nutrition and Metabolism. 2019. Vol. 2019, no. 2019, pp.1-8.
https://search.emarefa.net/detail/BIM-1183605
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1183605
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر